Myoid angioendothelioma of the spleen mimicking metastatic disease in a patient with rectal cancer: a radiologic-pathologic correlation

被引:2
作者
Jang, Kyu Yun [1 ]
Chung, Myoung Ja [1 ]
Moon, Woo Sung [1 ]
Sohn, Myung Hee [2 ]
Hwang, Seung Bae [3 ]
Lee, Min Ro [4 ]
Lee, Ho [5 ]
Park, Ho Sung [1 ]
机构
[1] Chonbuk Natl Univ, Sch Med, Res Inst Endocrine Sci, Dept Pathol,Res Inst Clin Med, Jeonju 561180, Jeonbuk, South Korea
[2] Chonbuk Natl Univ, Sch Med, Res Inst Clin Med, Dept Nucl Med, Jeonju 561180, Jeonbuk, South Korea
[3] Chonbuk Natl Univ, Sch Med, Res Inst Clin Med, Dept Radiol, Jeonju 561180, Jeonbuk, South Korea
[4] Chonbuk Natl Univ, Sch Med, Res Inst Clin Med, Dept Surg, Jeonju 561180, Jeonbuk, South Korea
[5] Chonbuk Natl Univ, Sch Med, Res Inst Clin Med, Dept Forens Med, Jeonju 561180, Jeonbuk, South Korea
基金
新加坡国家研究基金会;
关键词
Splenic neoplasms; Vascular neoplasms; Rectal neoplasms; Adenocarcinoma; FEATURES; CELLS;
D O I
10.1016/j.anndiagpath.2012.03.001
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Myoid angioendothelioma of the spleen is an uncommon, benign vascular tumor that is morphologically characterized by a composite of vascular spaces and stromal cells with myoid feature. Herein, we report a case of the myoid angioendothelioma of the spleen, concurrent with rectal adenocarcinoma. A 41-year-old woman presented with hematochezia for several weeks. Grossly, the rectal mass was a 2.5 x 2-cm ulcerative fungating lesion. The splenic mass was a 2.2 x 2-cm well-circumscribed lesion. Microscopically, the rectal mass was a well-differentiated adenocarcinoma that invaded into the pericolic adipose tissue. The splenic mass was composed of slit-like vascular spaces and fascicles of elongated stromal cells. Vascular endothelial cells were immunopositive for CD31, factor VIII-related antigen, and CD34 but negative for CD8. Stromal cells were immunopositive for smooth muscle actin but negative for desmin. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:108 / 112
页数:5
相关论文
共 12 条
[1]   Myoid angioendothelioma of the spleen in a child after successful treatment of a Wilms' tumour [J].
Chan, YF ;
Kumar, B ;
Auldist, A ;
Waters, K .
PATHOLOGY, 2005, 37 (02) :181-U4
[2]   PRIMARY ANGIOSARCOMA OF THE SPLEEN - A CLINICOPATHOLOGICAL STUDY OF 40 CASES [J].
FALK, S ;
KRISHNAN, J ;
MEIS, JM .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1993, 17 (10) :959-970
[3]   CT findings in primary vascular tumors of the spleen [J].
Ferrozzi, F ;
Bova, D ;
Draghi, F ;
Garlaschi, G .
AMERICAN JOURNAL OF ROENTGENOLOGY, 1996, 166 (05) :1097-1101
[4]   Myoid angioendothelioma of the spleen [J].
Karim, RZ ;
Ma-Wyatt, J ;
Cox, M ;
Scolyer, RA .
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 2004, 12 (01) :51-56
[5]  
Kraus MD, 1999, HISTOPATHOLOGY, V35, P328
[6]   Sclerosing angiomatoid nodular transformation (SANT) - Report of 25 cases of a distinctive benign splenic lesion [J].
Martel, M ;
Cheuk, W ;
Lombardi, L ;
Lifschitz-Mercer, B ;
Chan, JKC ;
Rosai, J .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2004, 28 (10) :1268-1279
[7]   HEMANGIOPERICYTOMA OF THE SPLEEN [J].
NEILL, JSA ;
PARK, HK .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1991, 95 (05) :680-683
[8]  
PINKUS GS, 1986, AM J PATHOL, V123, P440
[9]   EPITHELIOID AND SPINDLE-CELL HEMANGIOENDOTHELIOMA OF THE SPLEEN - REPORT OF A DISTINCTIVE SPLENIC VASCULAR NEOPLASM OF CHILDHOOD [J].
SUSTER, S .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1992, 16 (08) :785-792
[10]  
TOCCANIERPELTE MF, 1987, AM J PATHOL, V129, P109