Catalytic Enantioconvergent Decarboxylative Allylic Alkylation of Allyl Indolenin-3-carboxylates

被引：28

作者：

Kaiser, Thomas M. ^{[1
]}

Yang, Jiong ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Chem, College Stn, TX 77843 USA

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 2013卷 / 19期

基金：

美国国家科学基金会;

关键词：

Enantioconvergent reactions; Palladium; Chirality; Allylic compounds; Boranes; KINETIC ASYMMETRIC TRANSFORMATION; ENANTIOSELECTIVE CONSTRUCTION; DE-EPIMERIZATION; N-ALLOC; PYRROLOINDOLINES; CASCADE; RACEMIZATION; ARYLATION; DEAROMATIZATION; ALCOHOLS;

D O I：

10.1002/ejoc.201300515

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catalytic enantioconvergent process has been developed for the conversion of racemic allyl indolenin-3-carboxylates into enantiomerically enriched C3-quaternary indolenines. A Pd-catalyzed decarboxylative allylic alkylation reaction was employed for both stereoablation of the racemic allyl indolenin-3-carboxylates and enantioselective formation of the quaternary carbon center.

引用

页码：3983 / 3987

页数：5

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