Empathy Moderates the Effect of Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex on Costly Punishment

被引:32
作者
Bruene, Martin [1 ]
Scheele, Dirk [2 ]
Heinisch, Christine [1 ]
Tas, Cumhur [1 ]
Wischniewski, Julia [1 ]
Guentuerkuen, Onur [3 ]
机构
[1] Ruhr Univ Bochum, Landschaftsverband Westfalen Lippe Univ Hosp, Res Dept Cognit Neuropsychiat & Psychiat Prevent, Bochum, Germany
[2] Univ Bonn, Dept Psychol, Bonn, Germany
[3] Ruhr Univ Bochum, Dept Biopsychol, Fac Psychol, Bochum, Germany
关键词
ALTRUISTIC PUNISHMENT; DECISION-MAKING; ULTIMATUM GAME; NEURAL BASIS; PSYCHOPATHY; COOPERATION; EVOLUTION; CHOICE; BASES;
D O I
10.1371/journal.pone.0044747
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Humans incur considerable costs to punish unfairness directed towards themselves or others. Recent studies using repetitive transcranial magnetic stimulation (rTMS) suggest that the right dorsolateral prefrontal cortex (DLPFC) is causally involved in such strategic decisions. Presently, two partly divergent hypotheses are discussed, suggesting either that the right DLPFC is necessary to control selfish motives by implementing culturally transmitted social norms, or is involved in suppressing emotion-driven prepotent responses to perceived unfairness. Accordingly, we studied the role of the DLPFC in costly (i.e. third party) punishment by applying rTMS to the left and right DLPFC before playing a Dictator Game with the option to punish observed unfair behavior (DG-P). In addition, sham stimulation took place. Individual differences in empathy were assessed with the German version of the Interpersonal Reactivity Index. Costly punishment increased (non-significantly) upon disruption of the right - but not the left - DLPFC as compared to sham stimulation. However, empathy emerged as a highly significant moderator variable of the effect of rTMS over the right, but not left, DLPFC, suggesting that the right DLPFC is involved in controlling prepotent emotional responses to observed unfairness, depending on individual differences in empathy.
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页数:8
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