Trefoil Factor Family Member 2 (TFF2) as an Inflammatory-Induced and Anti-Inflammatory Tissue Repair Factor

被引：9

作者：

Ghanemi, Abdelaziz ^{[1
,2
]}

Yoshioka, Mayumi ^{[2
]}

St-Amand, Jonny ^{[1
,2
]}

机构：

[1] Laval Univ, Fac Med, Dept Mol Med, Quebec City, PQ G1V 0A6, Canada

[2] Univ Laval, Funct Genom Lab, CHU Quebec, Res Ctr,Endocrinol & Nephrol Axis, Quebec City, PQ G1V 4G2, Canada

来源：

ANIMALS | 2020年 / 10卷 / 09期

关键词：

trefoil factor family member 2 (TFF2); inflammation; tissue repair; SPASMOLYTIC POLYPEPTIDE; ACID-SECRETION; GASTRIC-MUCOSA; CELL LINEAGE; MICE LACKING; EXPRESSION; RECEPTOR; PEPTIDE; ALPHA; ACTIVATION;

D O I：

10.3390/ani10091646

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Trefoil factor family member 2 (TFF2) is known for its involvement in mucosal repair. Whereas it is overexpressed during inflammatory processes, adding TFF2 leads to an anti-inflammatory effect that would contribute to create the microenvironment required for tissue repair. These properties present TFF2 with a homeostatic pattern during inflammatory processes as illustrated by selected examples.

引用

页数：6

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