Trefoil Factor Family Member 2 (TFF2) as an Inflammatory-Induced and Anti-Inflammatory Tissue Repair Factor

被引：10
作者：
Ghanemi, Abdelaziz [1 ,2 ]
Yoshioka, Mayumi [2 ]
St-Amand, Jonny [1 ,2 ]
机构：
[1] Laval Univ, Fac Med, Dept Mol Med, Quebec City, PQ G1V 0A6, Canada
[2] Univ Laval, Funct Genom Lab, CHU Quebec, Res Ctr,Endocrinol & Nephrol Axis, Quebec City, PQ G1V 4G2, Canada
来源：
ANIMALS | 2020年 / 10卷 / 09期
关键词：
trefoil factor family member 2 (TFF2); inflammation; tissue repair; SPASMOLYTIC POLYPEPTIDE; ACID-SECRETION; GASTRIC-MUCOSA; CELL LINEAGE; MICE LACKING; EXPRESSION; RECEPTOR; PEPTIDE; ALPHA; ACTIVATION;
D O I：
10.3390/ani10091646
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
Trefoil factor family member 2 (TFF2) is known for its involvement in mucosal repair. Whereas it is overexpressed during inflammatory processes, adding TFF2 leads to an anti-inflammatory effect that would contribute to create the microenvironment required for tissue repair. These properties present TFF2 with a homeostatic pattern during inflammatory processes as illustrated by selected examples.
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页数：6
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