Chemical Constituents of the Root of Jasminum giraldii

被引：29

作者：

Yue, Zhenggang ^{[1
,2
]}

Qin, Hui ^{[3
]}

Li, Yuhua ^{[1
,2
]}

Sun, Yang ^{[1
,2
]}

Wang, Zhipeng ^{[1
,2
]}

Yang, Tiehong ^{[1
,2
]}

Liu, Li ^{[1
,2
]}

Wang, Minchang ^{[4
]}

Feng, Feng ^{[3
]}

Mei, Qibing ^{[1
,2
]}

机构：

[1] Fourth Mil Med Univ, Sch Pharm, Dept Pharmacol, Xian 710032, Shaanxi, Peoples R China

[2] Fourth Mil Med Univ, Collaborat Innovat Ctr Chinese Med Qingba Mt, Xian 710032, Shaanxi, Peoples R China

[3] China Pharmaceut Univ, Dept Nat Med Chem, Nanjing 210009, Jiangsu, Peoples R China

[4] Xian Modern Chem Res Inst, Xian 710032, Shaanxi, Peoples R China

来源：

MOLECULES | 2013年 / 18卷 / 04期

关键词：

Jasminum giraldii; oleaceae; chemical constituents; cytotoxic activity; SECOIRIDOID GLUCOSIDES;

D O I：

10.3390/molecules18044766

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new compounds, ethylconiferin (1) and (-)-lariciresinol 4-(6'''-O-cinnamyl-beta-D-glucopyranoside) (2), along with the three known compounds (+)-pinoresinol (3), (+)-cycloolivil (4), nobiletin (5), were isolated from the root of Jasminum girialdii. All these compounds were isolated for the first time from this source. Their structures were elucidated on the basis of extensive spectroscopic analysis and chemical methods. In addition, the in vitro cytotoxic activity of these compounds was evaluated. The results showed that none of the compounds had any significant inhibitory activities on the proliferation of HCT-116 and SW-620 cells.

引用

页码：4766 / 4775

页数：10

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