Reactions Induced by Platelet Transfusions

被引:74
作者
Kiefel, Volker [1 ]
机构
[1] Univ Klinikum Rostock, Abt Transfus Med, D-18057 Rostock, Germany
关键词
Platelet transfusion; Transfusion reactions; Bacterial contamination of blood products; Hemolytic transfusion reactions; Febrile nonhemolytic transfusion reactions;
D O I
10.1159/000151350
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Platelet transfusions play a central role in therapeutic regimens for patients with hematologic/oncologic diseases who develop severe thrombocytopenia either in the course of their disease or following cytostatic therapy. Like other blood components, platelet transfusions have achieved a high degree of safety as far as transmission of viral diseases is concerned. However, transfusion of platelet concentrates is accompanied by a high frequency of febrile and anaphylactoid reactions. In rare cases, recipients of platelet concentrates are threatened by severe reactions as septic complications due to bacterial contamination of platelet concentrates, transfusion-related acute lung injury and severe anaphylactic episodes.
引用
收藏
页码:354 / 358
页数:5
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