Statins and heart failure

被引：10
作者：
Filippatos, Theodosios D. [1 ]
Mikhailidis, Dimitri P. [1 ]
机构：
[1] UCL, Dept Clin Biochem, Vasc Dis Prevent Clin, London NW3 2QG, England
来源：
ANGIOLOGY | 2008年 / 59卷
关键词：
statins; heart failure; mortality; prevention;
D O I：
10.1177/0003319708319643
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Retrospective Studies show that statin use prevents congestive heart failure and decreases mortality in patients with congestive heart failure; however, only one prospective study is available. In the Controlled Rosuvastatin Multinational Trial in Heart Failure study, rosuvastatin (10 mg/d) was compared with placebo in patients with advanced coronary heart disease-related congestive heart failure. There was no significant difference between rosuvastatin and placebo except for hospitalization rates. Statins must be given to all patients with coronary heart disease as early as possible because they may not work in patients with advanced congestive heart failure.
引用
收藏
页码：58S / 61S
页数：4
相关论文
共 26 条
[1]   The effects of cholesterol lowering with simvastatin on cause-specific mortality and on cancer incidence in 20,536 high-risk people: a randomised placebo-controlled trial [ISRCTN48489393] [J].
Armitage, Jane ;
Collins, Rory ;
Bowman, Louise ;
Parish, Sarah ;
Sleight, Peter ;
Peto, Richard ;
Meade, T. ;
Youngman, L. ;
Buxton, M. ;
de Bono, D. ;
George, C. ;
Fuller, J. ;
Keech, A. ;
Mansfield, A. ;
Pentecost, B. ;
Simpson, D. ;
Warlow, C. ;
McNamara, J. ;
O'Toole, L. ;
Doll, R. ;
Wilhelmsen, L. ;
Fox, K. M. ;
Hill, C. ;
Sandercock, P. .
BMC MEDICINE, 2005, 3 (1)
[2]  
*ASTRAZENECA, CREST OUTC STUD JUPI
[3]   Treatment with atorvastatin to the National Cholesterol Educational Program goal versus 'usual' care in secondary coronary heart disease prevention - The GREek Atorvastatin and Coronary-heart-disease Evaluation (GREACE) Study [J].
Athyros, VG ;
Papageorgiou, AA ;
Mercouris, BR ;
Athyrou, VV ;
Symeonidis, AN ;
Basayannis, EO ;
Demitriadis, DS ;
Kontopoulos, AG .
CURRENT MEDICAL RESEARCH AND OPINION, 2002, 18 (04) :220-228
[4]   Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [J].
Cleeman, JI ;
Grundy, SM ;
Becker, D ;
Clark, LT ;
Cooper, RS ;
Denke, MA ;
Howard, WJ ;
Hunninghake, DB ;
Illingworth, DR ;
Luepker, RV ;
McBride, P ;
McKenney, JM ;
Pasternak, RC ;
Stone, NJ ;
Van Horn, L ;
Brewer, HB ;
Ernst, ND ;
Gordon, D ;
Levy, D ;
Rifkind, B ;
Rossouw, JE ;
Savage, P ;
Haffner, SM ;
Orloff, DG ;
Proschan, MA ;
Schwartz, JS ;
Sempos, CT ;
Shero, ST ;
Murray, EZ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19) :2486-2497
[5]   Clinical trials update from the European Society of Cardiology heart failure meeting: TNT subgroup analysis, darbepoetin alfa, FERRIC-HF and KW-3902 [J].
Coletta, Alison P. ;
Tin, Lwin ;
Loh, P. Huan ;
Clark, Andrew L. ;
Cleland, John G. F. .
EUROPEAN JOURNAL OF HEART FAILURE, 2006, 8 (05) :547-549
[6]  
Collins R, 2002, LANCET, V360, P7, DOI 10.1016/S0140-6736(02)09327-3
[7]   Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes - Phase Z of the A to Z trial [J].
de Lemos, JA ;
Blazing, MA ;
Wiviott, SD ;
Lewis, EF ;
Fox, KAA ;
White, HD ;
Rouleau, JL ;
Pedersen, TR ;
Gardner, LH ;
Mukherjee, R ;
Ramsey, KE ;
Palmisano, J ;
Bilheimer, DW ;
Pfeffer, MA ;
Califf, RM ;
Braunwald, E .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (11) :1307-1316
[8]   Statin therapy and risks for death and hospitalization in chronic heart failure [J].
Go, Alan S. ;
Lee, Wendy Y. ;
Yang, Jingrong ;
Lo, Joan C. ;
Gurwitz, Jerry H. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2006, 296 (17) :2105-2111
[9]  
Grundy Scott M, 2004, J Am Coll Cardiol, V44, P720, DOI 10.1016/j.jacc.2004.07.001
[10]  
Kjekshus J, 1997, J Card Fail, V3, P249, DOI 10.1016/S1071-9164(97)90022-1
123