Severe aplastic anemia in a patient with rheumatoid arthritis after introduction of etanercept

被引：0

作者：

Horai, Yoshiro ^{[1
]}

Miyamura, Tomoya ^{[1
]}

Shimada, Karin ^{[1
]}

Ishida, Motoko ^{[1
]}

Takahama, Soichiro ^{[1
]}

Minami, Rumi ^{[1
]}

Yamamoto, Masahiro ^{[1
]}

Suematsu, Eiichi ^{[1
]}

机构：

[1] Natl Hosp Org Kyushu Med Ctr, Dept Internal Med & Rheumatol, Clin Res Ctr, Chuo Ku, Fukuoka 8108563, Japan

来源：

CENTRAL EUROPEAN JOURNAL OF MEDICINE | 2012年 / 7卷 / 05期

关键词：

Aplastic anemia; Rheumatoid arthritis; Etanercept; EPSTEIN-BARR-VIRUS; TNF-ALPHA; METHOTREXATE; INHIBITORS; INFLIXIMAB;

D O I：

10.2478/s11536-012-0037-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 73-year-old female, diagnosed with rheumatoid arthritis (RA), complicated with severe levels of joint destruction, started etanercept (ETN) because of high persistent RA disease activity. Although her articular symptoms dramatically improved, she developed marked pancytopenia after the introduction of ETN. Bone marrow aspirate specimen revealed hypocellular marrow in three hematopoietic series without atypical findings, which was compatible with aplastic anemia (AA). This is a rare case of severe pancytopenia due to AA presumably induced by ETN.

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收藏

页码：650 / 654

页数：5

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