Mother-to-child transmission of hepatitis B and C virus: review of the epidemiology and current treatment options

被引:1
作者
Sarpel, Dost [1 ]
Kushner, Tatyana [2 ]
Carter, Danielle [2 ]
Huisman, Tsipora [3 ]
Chiu, Sophia [3 ]
Dieterich, Douglas [2 ]
机构
[1] Icahn Sch Med Mt Sinai, Div Infect Dis, Dept Med, Mt Sinai West St Lukes Campus,1000 10th Ave, New York, NY 10019 USA
[2] Icahn Sch Med Mt Sinai, Inst Liver Med, Dept Med, Annenberg 5-04,1468 Madison Ave Box 1123, New York, NY 10029 USA
[3] Icahn Sch Med Mt Sinai, Dept Med, 1 Gustave L Levy Pl, New York, NY 10029 USA
关键词
chronic hepatitis B; chronic hepatitis C; mother-to-child transmission; TENOFOVIR DISOPROXIL FUMARATE; HCV VERTICAL TRANSMISSION; BREAST-FEEDING INFANTS; UNITED-STATES; PERINATAL TRANSMISSION; ANTIVIRAL THERAPY; NATURAL-HISTORY; PREGNANT-WOMEN; YOUNG-ADULTS; CESAREAN-SECTION;
D O I
10.2217/fvl-2017-0069
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Hepatitis B and C viruses are the leading causes of liver-related morbidity and mortality throughout the world. Hepatitis B virus is predominantly transmitted perinatally, particularly in endemic areas. The rate of mother-to-child transmission of hepatitis C virus is on the rise, largely due to the increasing opioid epidemic. While there are guidelines established for the screening and treatment of pregnant females at risk for chronic hepatitis B infection, there no such guidelines or treatment options available in pregnant females with chronic hepatitis C infection. This review examines the epidemiology of mother-to-child transmission of chronic hepatitis B and C as well as the current treatment options during pregnancy and breastfeeding for both.
引用
收藏
页码:43 / 52
页数:10
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