Features of the metabolic syndrome and the risk of cardiovascular disease

被引:0
作者
Lamarche, B [1 ]
St-Pierre, AC [1 ]
机构
[1] Univ Laval, Inst Nutraceut & Funct Foods, Ste Foy, PQ G1K 7P4, Canada
关键词
metabolic syndrome; dyslipidemia; LDL size; waist girth; obesity; LIPOPROTEIN PARTICLE-SIZE; APOLIPOPROTEIN-B LEVELS; ISCHEMIC-HEART-DISEASE; INSULIN-RESISTANCE; MYOCARDIAL-INFARCTION; FASTING INSULIN; DENSE LDL; ALL-CAUSE; A-I; CHOLESTEROL;
D O I
10.1080/13547500500216579
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The metabolic syndrome is being increasingly recognized as an important risk factor for cardiovascular disease (CVD). While several clinical definitions have been proposed to identify patients with this syndrome, additional metabolic markers may be considered to improve one's ability to assess and predict the risk of CVD in this population. The objective of this short review is to provide an overview of the risk of CVD associated with specific features of the metabolic syndrome. The extent to which these markers may be used one day in clinical practice in primary prevention is also briefly discussed.
引用
收藏
页码:S37 / S43
页数:7
相关论文
共 33 条
[1]  
[Anonymous], 1999, Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications: Report of a WHO Consultation-Part 1: Diagnosis and Classification of Diabetes Mellitus
[2]  
[Anonymous], 1923, Z Inn Med
[3]   Insulin resistance quantification by fasting insulin plasma values and HOMA index in a non-diabetic population [J].
Ascaso, JF ;
Romero, P ;
Real, JT ;
Priego, A ;
Valdecabres, C ;
Carmena, R .
MEDICINA CLINICA, 2001, 117 (14) :530-533
[4]   Low-density lipoprotein particle size, triglycerides, and high-density lipoprotein cholesterol as risk factors for coronary heart disease in older Japanese-American men [J].
Austin, MA ;
Rodriguez, BL ;
McKnight, B ;
McNeely, MJ ;
Edwards, KL ;
Curb, JD ;
Sharp, DS .
AMERICAN JOURNAL OF CARDIOLOGY, 2000, 86 (04) :412-416
[5]  
Best J D, 1990, Horm Metab Res Suppl, V24, P60
[6]   Abdominal fat and insulin resistance in normal and overweight women - Direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM [J].
Carey, DG ;
Jenkins, AB ;
Campbell, LV ;
Freund, J ;
Chisholm, DJ .
DIABETES, 1996, 45 (05) :633-638
[7]   Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [J].
Cleeman, JI ;
Grundy, SM ;
Becker, D ;
Clark, LT ;
Cooper, RS ;
Denke, MA ;
Howard, WJ ;
Hunninghake, DB ;
Illingworth, DR ;
Luepker, RV ;
McBride, P ;
McKenney, JM ;
Pasternak, RC ;
Stone, NJ ;
Van Horn, L ;
Brewer, HB ;
Ernst, ND ;
Gordon, D ;
Levy, D ;
Rifkind, B ;
Rossouw, JE ;
Savage, P ;
Haffner, SM ;
Orloff, DG ;
Proschan, MA ;
Schwartz, JS ;
Sempos, CT ;
Shero, ST ;
Murray, EZ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19) :2486-2497
[8]   Inflammation and cardiovascular disease:: is abdominal obesity the missing link? [J].
Després, JP .
INTERNATIONAL JOURNAL OF OBESITY, 2003, 27 (Suppl 3) :S22-S24
[9]   Hyperinsulinemia as an independent risk factor for ischemic heart disease [J].
Despres, JP ;
Lamarche, B ;
Mauriege, P ;
Cantin, B ;
Dagenais, GR ;
Moorjani, S ;
Lupien, PJ .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (15) :952-957
[10]   Prevalence of the metabolic syndrome among US adults - Findings from the Third National Health and Nutrition Examination Survey [J].
Ford, ES ;
Giles, WH ;
Dietz, WH .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 287 (03) :356-359