Does Large Needle Aspiration Biopsy Add Pain to the Thyroid Nodule Evaluation?

被引：12

作者：

Carpi, Angelo ^{[1
]}

Rossi, Giuseppe ^{[2
,3
]}

Nicolini, Andrea ^{[1
]}

Iervasi, Giorgio ^{[3
,4
]}

Russo, Matteo ^{[5
,6
]}

Mechanick, Jeffrey ^{[7
]}

机构：

[1] Univ Pisa, Dept Clin & Expt Med, Pisa, Italy

[2] CNR, Inst Clin Physiol, Natl Res Council, Unit epidemiol & Biostat, I-56100 Pisa, Italy

[3] G Monasterio Fdn, Pisa, Italy

[4] CNR, Inst Clin Physiol, Natl Res Council, I-56100 Pisa, Italy

[5] Univ Roma La Sapienza, Dept Expt Med, I-00185 Rome, Italy

[6] IRCCS San Raffaele Pisana, Dept Cellular & Mol Pathol, Rome, Italy

[7] Mt Sinai Sch Med, Div Endocrinol Diabet & Bone Dis, New York, NY USA

来源：

PLOS ONE | 2013年 / 8卷 / 03期

关键词：

PREOPERATIVE SELECTION; MICROFOLLICULAR NODULE; SUSPECTED CANCER; CYTOLOGY; PERFORMANCE; DIAGNOSIS; HISTOLOGY;

D O I：

10.1371/journal.pone.0058016

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Thyroid large needle aspiration biopsy is disregarded because it is thought to be associated with pain. This is in contrast with our 32 years long experience. We surveyed reports of pain in patients examined with fine needle aspiration biopsy (78, 87.2% women, mean age 59 years) or FNAB+large needle aspiration biopsy (48, 87.5% women, mean age 60 years). Each patient was questioned regarding a) no unpleasant sensation (score "0"); b) unpleasant sensation ("1"); c) mild pain (no analgesic used; "2"); or d) pain (analgesic used; "3"). The mean size of the needle used was for FNAB 22.3 +/- 0.7 or 20.8 +/- 1 gauge in the fine needle aspiration or fine needle aspiration plus large needle aspiration biopsy group, respectively (p<.0001). The number of percutaneous punctures was higher in the fine needle aspiration plus large needle aspiration biopsy group. However, the pain score in the fine needle aspiration biopsy or fine needle aspiration biopsy plus large needle aspiration biopsy group was not significantly different. Large needle aspiration biopsy after fine needle aspiration biopsy does not add any discomfort or pain and therefore in light of the demonstrable benefits, should be included in clinical algorithms for the evaluation of thyroid nodules.

引用

页数：3

共 21 条

[1]

[Anonymous], ENDOCR PRACT

[2] Galectin-3-expression analyses in the surgical selection of follicular thyroid nodules with indeterminate fine-needle aspiration cytology: a prospective multicentre study [J].