Cryptococcal Disease in the Era of "Test and Treat": Is There Cause for Concern?

被引：7

作者：

Abassi, Mahsa ^{[1
,2
]}

Rhein, Joshua ^{[1
,2
]}

Meya, David B. ^{[1
,2
,3
]}

Boulware, David R. ^{[2
]}

机构：

[1] Infect Dis Inst, POB 22148,Mulago Hosp Complex, Kampala, Uganda

[2] Univ Minnesota, Minneapolis, MN USA

[3] Makerere Univ, Sch Med, Coll Hlth Sci, Kampala, Uganda

来源：

OPEN FORUM INFECTIOUS DISEASES | 2018年 / 5卷 / 01期

关键词：

cryptococcal immune reconstitution syndrome; HIV; test and treat; ANTIRETROVIRAL THERAPY; INDIVIDUALS; INFECTIONS;

D O I：

10.1093/ofid/ofx274

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Treatment of cryptococcosis requires deferred initiation of anti-retroviral therapy (ART). Early ART initiation may be detrimental in the context of cryptococcal infection by increasing the risk of immune reconstitution inflammatory syndrome (IRIS). We present 3 cases where early ART initiation in the presence of unrecognized cryptococcal disease had fatal outcomes.

引用

页数：4

共 17 条

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