CNS vasculopathies: Challenging mimickers of primary angiitis of the central nervous system

被引:11
作者
Cho, Tracey A. [1 ]
Jones, Ann [1 ]
机构
[1] 200 Hawkins Dr, Iowa City, IA 52242 USA
来源
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2020年 / 34卷 / 04期
关键词
Primary angiitis of the central nervous system; Cerebral vasculitis; Cerebral vasculopathy; Reversible cerebral vasoconstriction syndrome; Sneddon's syndrome; Amyloid-beta-related angiopathy; Susac syndrome; Neurosarcoidosis; TERM-FOLLOW-UP; SNEDDON-SYNDROME; GRANULOMATOUS-ANGIITIS; AMYLOID ANGIOPATHY; SUSAC-SYNDROME; CEREBROVASCULAR LESIONS; CEREBRAL MICROBLEEDS; NOTCH3; MUTATIONS; CADASIL; NEUROSARCOIDOSIS;
D O I
10.1016/j.berh.2020.101569
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Primary angiitis of the central nervous system (CNS) is an inflammatory vasculopathy affecting the brain and spinal cord. It is a difficult diagnosis to make because of its insidious nonspecific course and its multiple mimics. This review identifies and discusses some noninfectious mimickers of primary CNS angiitis, including: reversible cerebral vasoconstriction syndrome, Sneddon's Syndrome, amyloid-beta-related angiopathy, Susac Syndrome, and neurosarcoidosis. Each condition will be reviewed in terms of epidemiology, pathology, clinical presentation, diagnostic approach, and treatment. Distinguishing these mimics from the primary angiitis of the CNS is important for proper treatment and prognosis. (C) 2020 Elsevier Ltd. All rights reserved.
引用
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页数:16
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