Nucleus or cytoplasm? The mysterious case of SIRT1's subcellular localization

被引:38
作者
Bai, Wenlong [1 ]
Zhang, Xiaohong [2 ]
机构
[1] Univ S Florida, Morsani Coll Med, Dept Pathol & Cell Biol, Tampa, FL USA
[2] Karmanos Canc Inst, Dept Oncol, 4100 John R St, Detroit, MI 48201 USA
关键词
fractionation; sirtuins; SIRT1; subcellular localization; CANCER-CELLS;
D O I
10.1080/15384101.2016.1237170
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:3337 / 3338
页数:2
相关论文
共 7 条
  • [1] A Biotin Switch-Based Proteomics Approach Identifies 14-3-3ζ as a Target of Sirt1 in the Metabolic Regulation of Caspase-2
    Andersen, Joshua L.
    Thompson, J. Will
    Lindblom, Kelly R.
    Johnson, Erika S.
    Yang, Chih-Sheng
    Lilley, Lauren R.
    Freel, Christopher D.
    Moseley, M. Arthur
    Kornbluth, Sally
    [J]. MOLECULAR CELL, 2011, 43 (05) : 834 - 842
  • [2] Byles V, 2010, INT J BIOL SCI, V6, P599
  • [3] SIRT1, Is It a Tumor Promoter or Tumor Suppressor?
    Deng, Chu-Xia
    [J]. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2009, 5 (02): : 147 - 152
  • [4] Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
    Imai, S
    Armstrong, CM
    Kaeberlein, M
    Guarente, L
    [J]. NATURE, 2000, 403 (6771) : 795 - 800
  • [5] Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases
    Imai, Shin-ichiro
    Guarente, Leonard
    [J]. TRENDS IN PHARMACOLOGICAL SCIENCES, 2010, 31 (05) : 212 - 220
  • [6] Janus-faced role of SIRT1 in tumorigenesis
    Song, Na-Young
    Surh, Young-Joon
    [J]. NUTRITION AND PHYSICAL ACTIVITY IN AGING, OBESITY, AND CANCER, 2012, 1271 : 10 - 19
  • [7] Macromolecular crowding effect is critical for maintaining SIRT1's nuclear localization in cancer cells
    Sun, Lidong
    Fang, Jia
    [J]. CELL CYCLE, 2016, 15 (19) : 2647 - 2655