Lithium treatment at 52

被引:94
作者
Schou, M [1 ]
机构
[1] Hosp Psychiat, DK-8240 Risskov, Denmark
关键词
lithium prophylaxis; side effects; compliance; prophylactic alternatives; suicide prevention;
D O I
10.1016/S0165-0327(01)00380-9
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The paper reviews briefly and comments in detail on selected events in the history of lithium treatment. The events include Cade's discovery of lithium's antimanic action, the discovery and establishment of its prophylactic action, the ensuing debate, amelioration and prevention of side effects and risks, use during pregnancy, non-compliance, selection of patients, information and instruction, the question whether new and better prophylactic agents are about to oust lithium, the use of combination treatment, the effect of lithium on suicidal behavior, the benefits of prophylactic lithium treatment, and the design of future comparative trials. (C) 2001 Elsevier Science BY. All rights reserved.
引用
收藏
页码:21 / 32
页数:12
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