A rationale for the targeted treatment of oligometastases with radiotherapy

被引：105
作者：
MacDermed, Dhara M. [1 ]
Weichselbaum, Ralph R. [1 ,2 ,3 ]
Salama, Joseph K. [1 ,2 ,3 ]
机构：
[1] Univ Chicago, Dept Radiat & Cellular Oncol, Chicago, IL 60637 USA
[2] Univ Chicago, Canc Res Ctr, Chicago, IL 60637 USA
[3] Univ Chicago, Ludwig Ctr Metastasis Res, Chicago, IL 60637 USA
来源：
JOURNAL OF SURGICAL ONCOLOGY | 2008年 / 98卷 / 03期
关键词：
oligometastatic; stereotactic body radiotherapy; biology of metastases;
D O I：
10.1002/jso.21102
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
An oligometastatic state has been proposed wherein patients with metastases limited in number and location may benefif from local therapy directed at all known sites of metastases. We describe here the clinical and biological basis for the oligometastatic state. We present evidence for a potentially curative approach to patients with oligometastases using stereotactic body radiotherapy (SBRT) and we review the literature for SBRT directed at specific metastatic sites in the lung, liver and multiple organs.
引用
收藏
页码：202 / 206
页数：5
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