Atypical M-protein localization in protein electrophoresis in a patient with multiple myeloma

被引：0

作者：

Yildirim, Naciye Demirel ^{[1
]}

Ayer, Mesut ^{[1
]}

Hatipoglu, Esra ^{[1
]}

Kucukkaya, Reyhan Diz ^{[1
]}

Yenerel, Mustafa Nuri ^{[1
]}

Nalcaci, Meliha ^{[1
]}

机构：

[1] Istanbul Univ, Fac Med, Sect Hematol, Dept Internal Med, TR-34390 Istanbul, Turkey

来源：

TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI | 2008年 / 25卷 / 01期

关键词：

blood protein electrophoresis; multiple myeloma; paraproteinemias;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Monoclonal gammopathy is a group of B-cell disorders resulting in the secretion of a specific and unique monoclonal immunoglobulin (M-component). The best method for detecting a monoclonal protein is high resolution agarose gel electrophoresis. This test detects abnormalities in the migration of the proteins on electrophoresis and can be performed with samples of serum or urine. An M-protein is usually visible as a localized band on agarose gel electrophoretic peak in the beta, gamma, or rarely in the alpha-2 globulin region of the densitometer tracing. Here, we presented a multiple myeloma patient with IgA kappa paraprotein showing an M spike in the alpha-2 globulin region in agarose gel electrophoresis.

引用

页码：56 / 59

页数：4

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