Effect of orange peel essential oil on oxidative stress in AOM animals

被引：16
作者：
Lv, Yun-Xia [1 ]
Zhao, Su-Ping [1 ]
Zhang, Jun-Yi [1 ]
Zhang, Hua [1 ]
Xie, Zhi-Hai [1 ]
Cai, Geng-Ming [1 ]
Jiang, Wei-Hong [1 ]
机构：
[1] Cent S Univ, Xiangya Hosp, Dept Otolaryngol Head & Neck, Changsha 410008, Hunan, Peoples R China
来源：
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2012年 / 50卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Microcapsules; Immunity; Essential oil; Acute otitis media; Oxidative injury; POLY(VINYL ALCOHOL) MICROCAPSULES; NITRIC-OXIDE SYNTHASE; MIDDLE-EAR; RESPIRATORY VIRUSES; OTITIS-MEDIA; FISH-OIL; MICROENCAPSULATION; SUPEROXIDE; RADICALS; RELEASE;
D O I：
10.1016/j.ijbiomac.2012.02.002
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The processing parameters of pump speed, inlet air temperature, outlet air temperature and homogenization pressure were evaluated. Encapsulation efficiency is high with a satisfied releasing rate. Then, acute otitis media (AOM) animal model was built and diet containing orange peel essential oil microcapsules were administrated to AOM animals. Pharmacological test showed that orange peel essential oil treatment could decrease serum and cochlea malondialdehyde (MDA), immunoglobulins A (IgA), immunoglobulins G (IgG), immunoglobulins M (IgM) levels and increase antioxidant enzymes activities. It can be concluded that orange peel essential oil treatment could decrease oxidative injury in acute otitis media rats. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：1144 / 1150
页数：7
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