Recent advances of biofuels and biochemicals production from sustainable resources using co-cultivation systems

被引:51
作者
Jiang, Yujia [1 ]
Wu, Ruofan [1 ]
Zhou, Jie [1 ,2 ]
He, Aiyong [3 ]
Xu, Jiaxing [3 ]
Xin, Fengxue [1 ,2 ]
Zhang, Wenming [1 ,2 ]
Ma, Jiangfeng [1 ,2 ]
Jiang, Min [1 ,2 ]
Dong, Weiliang [1 ,2 ]
机构
[1] Nanjing Tech Univ, State Key Lab Mat Oriented Chem Engn, Coll Biotechnol & Pharmaceut Engn, Puzhu South Rd 30, Nanjing 211800, Jiangsu, Peoples R China
[2] Nanjing Tech Univ, Jiangsu Natl Synerget Innovat Ctr Adv Mat SICAM, Nanjing 211800, Jiangsu, Peoples R China
[3] Huaiyin Normal Univ, Jiangsu Key Lab Biomass Based Energy & Enzyme Tec, Huaian 223300, Peoples R China
基金
中国国家自然科学基金;
关键词
Microbial consortia; Co-cultivation; Biofuels; Chemicals; Natural compounds; Sustainable resources; ENGINEERING MICROBIAL CONSORTIA; CLOSTRIDIUM-THERMOCELLUM; ETHANOL-PRODUCTION; BUTANOL PRODUCTION; METABOLIC PATHWAY; WASTE-WATER; N-BUTANOL; COCULTURE; ACID; BIOSYNTHESIS;
D O I
10.1186/s13068-019-1495-7
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Microbial communities are ubiquitous in nature and exhibit several attractive features, such as sophisticated metabolic capabilities and strong environment robustness. Inspired by the advantages of natural microbial consortia, diverse artificial co-cultivation systems have been metabolically constructed for biofuels, chemicals and natural products production. In these co-cultivation systems, especially genetic engineering ones can reduce the metabolic burden caused by the complex of metabolic pathway through labor division, and improve the target product production significantly. This review summarized the most up-to-dated co-cultivation systems used for biofuels, chemicals and nature products production. In addition, major challenges associated with co-cultivation systems are also presented and discussed for meeting further industrial demands.
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页数:12
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