Epidemiology of suicide in bipolar disorders: a systematic review of the literature

被引:276
作者
Pompili, Maurizio [1 ]
Gonda, Xenia [2 ]
Serafini, Gianluca [1 ]
Innamorati, Marco [1 ]
Sher, Leo [3 ,4 ]
Amore, Mario [5 ]
Rihmer, Zoltan [2 ]
Girardi, Paolo [1 ,6 ]
机构
[1] Univ Roma La Sapienza, St Andrea Hosp, Dept Neurosci Mental Hlth & Sensory Organs, Suicide Prevent Ctr, I-00189 Rome, Italy
[2] Semmelweis Univ, Dept Clin & Theoret Mental Hlth, Kutvolgyi Clin Ctr, H-1085 Budapest, Hungary
[3] Mt Sinai Sch Med, New York, NY USA
[4] James J Peters Vet Adm Med Ctr, New York, NY USA
[5] Univ Genoa, Sect Psychiat, Dept Neurosci Rehabil Ophthalmol Genet Maternal &, Genoa, Italy
[6] Villa Rosa Med Res Ctr, Viterbo, Italy
关键词
adults; bipolar disorder; completed suicides; risk factors; suicide rates; MAJOR DEPRESSION; RISK-FACTORS; ANXIETY DISORDERS; COMPLETED SUICIDE; MIXED-STATE; FOLLOW-UP; LITHIUM; BEHAVIOR; PREVALENCE; MORTALITY;
D O I
10.1111/bdi.12087
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: Suicidal behavior is a major public health problem worldwide, and its prediction and prevention represent a challenge for everyone, including clinicians. The aim of the present paper is to provide a systematic review of the existing literature on the epidemiology of completed suicides in adult patients with bipolar disorder (BD). Methods: We performed a Pubmed/Medline, Scopus, PsycLit, PsycInfo, and Cochrane database search to identify all relevant papers published between 1980 and 2011. A total of 34 articles meeting our inclusion criteria were included in the present review. Results: Several prospective follow-up contributions, many retrospective analyses, and a few psychological autopsy studies and review articles investigated the epidemiology of completed suicides in patients with BD. The main finding of the present review was that the risk for suicide among BD patients was up to 20-30 times greater than that for the general population. Conclusion: Special attention should be given to the characteristics of suicides in patients with BD. Better insight and understanding of suicide and suicidal risk in this very disabling illness should ultimately help clinicians to adequately detect, and thus prevent, suicidal acts in patients with BD.
引用
收藏
页码:457 / 490
页数:34
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