Electrocatalytic Oxidation of Acyclovir on Poly(p-Aminobenzene Sulfonic Acid) Film Modified Glassy Carbon Electrode

被引：25

作者：

Can, Saide ^{[1
]}

Yilmaz, Selehattin ^{[1
]}

Saglikoglu, Gulsen ^{[1
]}

Sadikoglu, Murat ^{[2
]}

Menek, Necati ^{[3
]}

机构：

[1] Canakkale Onsekiz Mart Univ, Fac Sci & Arts, Dept Chem, Canakkale, Turkey

[2] Gaziosmanpasa Univ, Fac Educ, Dept Sci Educ, Tokat, Turkey

[3] Ondokuz Mayis Univ, Fac Sci & Arts, Dept Chem, Samsun, Turkey

来源：

ELECTROANALYSIS | 2015年 / 27卷 / 10期

关键词：

p-Aminobenzene sulfonic acid; Modified-glassy carbon electrode; Electropolymerization; Electrocatalytic oxidation; Determination of acyclovir; Voltammetry; QUANTITATIVE-DETERMINATION; VOLTAMMETRIC DETERMINATION; ELECTROCHEMICAL-BEHAVIOR; ASCORBIC-ACID; PLASMA; SPECTROSCOPY; MECHANISM; DOPAMINE; GRAPHITE; DNA;

D O I：

10.1002/elan.201500102

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Acyclovir is an antiviral effective drug active compound. A glassy carbon electrode (GCE) was modified with an electropolymerized film of p-aminobenzene sulfonic acid (p-ABSA) in phosphate buffer solution (PBS). The polymer film-modified electrode was used to electrochemically detect acyclovir. Polymer film showed excellent electrocatalytic activity for the oxidation of acyclovir. The anodic peak potential value of the acyclovir at the poly(p-ABSA) modified glassy carbon electrode was 950mV obtained by DPV. A linear calibration curve for DPV analysis was constructed in the acyclovir concentration range 2x10(-7)-9x10(-6)molL(-1). Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 5.57x10(-8) and 1.85x10(-7)molL(-1) respectively. The proposed method exhibits good recovery and reproducibility.

引用

页码：2431 / 2438

页数：8

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