Therapeutic criteria in communicating childhood hydrocephalus

被引:0
作者
Rodriguez-Nunez, A. [1 ]
Somoza-Martin, M. [1 ]
Gomez-Lado, C. [1 ]
Eiris-Punal, J. [1 ]
Camina-Darriba, F. [2 ]
Rodriguez-Segade, S. [2 ]
Castro-Gago, M. [1 ]
机构
[1] Univ Hosp, Dept Pediat, Neuropediat Serv, Santiago De Compostela, Spain
[2] Univ Santiago de Compostela, Dept Biochem & Mol Biol, Santiago De Compostela, Spain
关键词
Cerebrospinal fluid; analysis; Hydrocephalus; Hypoxanthine; Xanthine; Uric acid; Ultrasonography; Doppler; transcranial;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Aim The aim of this study was to evaluate the usefulness of cerebral blood flow velocity in the middle cerebral artery measured by transcranial Doppler as criteria to therapeutic action in communicating hydrocephalic children. Methods. In eight non-tumoral communicating hydrocephalic infants, ranging from five to 18 months of age, monitored from 18 to 36 months (mean time of follow-up: 24.25 months), cerebrospinal fluid (CSF) oxypurines; (hypoxanthine and xanthine) and uric acid levels were compared by means of the Evans' index, the mean weekly increase in cranial circumference, and the transcranial Doppler measurements. Results. Results indicate that clinical (mean weekly increase in head circumference), radiological (Evans' index), biochemical (oxypurines and uric acid in the CSF), and hemodynamic (transcranial Doppler) criteria have the same role in monitoring infantile hydrocephalus. Conclusion. In conclusion the transcranial Doppler measurement can be done noninvasively and examinations can be repeated when needed, obtaining immediate results. Hence, it is the most adequate monitoring technique in clinical practice.
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页码:17 / 21
页数:5
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