Cryoballoon Ablation for Treatment of Atrial Fibrillation in a Chinese Population: Five-Year Outcomes and Predictors of Recurrence After a Single Procedure

被引:5
作者
Chen, Xiongbiao
Xia, Yu
Lin, Yuan
Li, Xiaofeng
Wang, Chun
Chen, Yanjun
Fang, Pihua
Liu, Jun
机构
[1] Department of Cardiology, Peking University Shenzhen Hospital, Shenzhen
[2] State Key Laboratory of Cardiovascular Disease, Cardiac Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing
[3] Department of General Practice, School of General Practice and Continuing Education, Capital Medical University, Beijing
来源
FRONTIERS IN CARDIOVASCULAR MEDICINE | 2022年 / 9卷
关键词
atrial fibrillation; cryoballoon; pulmonary vein isolation; long-term; follow-up; PULMONARY VEIN ISOLATION; RADIOFREQUENCY ABLATION; RESUMPTION; CONDUCTION; SUCCESS;
D O I
10.3389/fcvm.2022.836392
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BackgroundThe 5-year outcomes and predictors of atrial fibrillation (AF) recurrence following cryoballoon (CB) ablation in Chinese population remain scarce. Our aim was to report 5-year outcomes and predictors of AF recurrence following a single CB ablation procedure in a Chinese population. MethodsFrom December 2013 to August 2016, we included 256 consecutive patients (mean age: 58 +/- 10.9 years old; female: 41.0%) with paroxysmal or persistent AF successfully underwent first-generation CB ablation at Fuwai hospital in this prospective study. All patients were followed at least 5 years or when there was recurrent AF. Independent predictors of AF recurrence were determined by Cox proportional hazards regression analysis. ResultsThe 5-year success rate after pulmonary vein isolation (PVI) by a single procedure was 59.4%. The recurrence rate was the highest (14.5%) within the first year after the index procedure, and then stabilized. Patients with paroxysmal AF had a higher incidence of freedom from AF recurrence than patients with persistent AF (63.2% vs. 36.4%, log-rank P < 0.01). The overall incidence of complications related to CB ablation was 7.8%. Phrenic nerve injury (PNI) was the most common complication, with an incidence of 3.5%, and patients with PNI were recovered within the 1-year follow-up. Only persistent AF (HR 1.72, 95%CI 1.028-2.854, P < 0.05) was significantly and independently associated with an increased risk of AF recurrence after adjusting for other factors. ConclusionPulmonary vein isolation using CB ablation was safe and effective with an acceptable complication and 5-year success rate in a Chinese population with AF, and persistent AF was the independent predictor for 5-year AF recurrence after a single CB ablation procedure.
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页数:8
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