The Prognostic Value of Serum Gamma Glutamyl Transferase Activity on Admission in Patients With STEMI Undergoing Primary PCI

被引：25

作者：

Akpek, Mahmut ^{[1
]}

Elcik, Deniz ^{[1
]}

Kalay, Nihat ^{[1
]}

Yarlioglues, Mikail ^{[2
]}

Dogdu, Orhan ^{[3
]}

Sahin, Omer ^{[1
]}

Ardic, Idris ^{[4
]}

Oguzhan, Abdurrahman ^{[1
]}

Ergin, Ali ^{[1
]}

Kaya, Mehmet G. ^{[1
]}

机构：

[1] Erciyes Univ, Sch Med, Dept Cardiol, TR-38039 Kayseri, Turkey

[2] Yozgat Sorgun State Hosp, Dept Cardiol, Yozgat, Turkey

[3] Yozgat State Hosp, Dept Cardiol, Yozgat, Turkey

[4] Gaziantep Av Cengiz Gokcek Sate Hosp, Dept Cardiol, Gaziantep, Turkey

来源：

ANGIOLOGY | 2012年 / 63卷 / 08期

关键词：

ST elevation myocardial infarction; percutaneous coronary intervention; gamma glutamyl transferase; MYOCARDIAL-INFARCTION; OXIDATIVE STRESS; URIC-ACID; TRANSPEPTIDASE; CONTRAST;

D O I：

10.1177/0003319711431880

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

We assessed the association between serum gamma glutamyl transferase (GGT) activity with postprimary percutaneous coronary intervention (PCI) coronary flow and in-hospital major advanced cardiac events (MACEs) in patients with ST elevation myocardial infarction (STEMI). Patients with STEMI (n = 425; males 78%; mean age 60 +/- 13 years) were enrolled. Patients were divided into 3 GGT tertiles and 2 groups according to thrombolysis in myocardial infarction (TIMI) flow grade. The TIMI flow percentages were similar in the 3 GGT tertiles (32%, 45%, and 42%, respectively, P = .336). Total MACE increased with GGT tertiles (among tertiles, respectively; P < .001). The total MACE was significantly higher in impaired flow group than in normal flow group (23% vs 7%; P < .001). At multivariate analyses, serum GGT activity was an independent predictor of in-hospital MACE (odds ratio [OR] 1.12, 95% confidence interval [CI] 1.01-1.33; P < .001). In conclusion, serum GGT activity is associated with in-hospital MACE in patients with STEMI undergoing primary PCI.

引用

页码：579 / 585

页数：7

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