New Anticancer Drugs from Marine Cyanobacteria

被引：12
|
作者：
Russo, Patrizia [1 ]
Cesario, Alfredo [1 ,2 ]
机构：
[1] IRCCS San Raffaele Pisana, Lab Syst Approaches & Non Transmissible Dis, I-00166 Rome, Italy
[2] Univ Cattolica Sacro Cuore, Div Thorac Surg, I-00168 Rome, Italy
来源：
CURRENT DRUG TARGETS | 2012年 / 13卷 / 08期
关键词：
Apratoxins; bisebromoamide; coibamide; largazole; lyngbya; symploca; PHASE-II; APRATOXIN; POTENT; CYCLODEPSIPEPTIDE; DEPSIPEPTIDE; LARGAZOLE; DOLASTATIN-10; STRAINS; ORIGIN; CANCER;
D O I：
10.2174/138945012802009035
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Marine Cyanobacteria have raised growing attention as sources of bioactive "secondary metabolites" that originate from mixed biosynthetic pathways. Some of these molecules exhibit antitumour activities with unique mechanism of action. This mini-review focuses specifically on new molecules that may act as leads for novel drug development.
引用
收藏
页码：1048 / 1053
页数：6
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