Synthesis and Evaluation of SARS 3CL Protease Inhibitors Using the Serine Template

被引:0
|
作者
Takanuma, D. [1 ]
Akaji, K. [2 ]
Konno, H. [1 ]
机构
[1] Yamagata Univ, Grad Sch Sci & Technol, Dept Biochem Engn, Yonezawa, Yamagata, Japan
[2] Kyoto Pharmaceutcial Univ, Dept Med Chem, Yamashina Ku, Kyoto, Japan
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:S148 / S148
页数:1
相关论文
共 50 条
  • [31] Synthesis and SARS-CoV-2 3CL Protease Inhibitory Effects of Oxazolidinone Derivatives
    Zhao, Shengxian
    Wang, Chaojie
    Lu, Yiming
    Zhang, Xin
    Wu, Siyu
    Mao, Hui
    JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 2022, 33 (09) : 1134 - 1143
  • [32] Evaluation of peptide-aldehyde inhibitors using R188I mutant of SARS 3CL protease as a proteolysis-resistant mutant
    Akaji, Kenichi
    Konno, Hiroyuki
    Onozuka, Mari
    Makino, Ayumi
    Saito, Hiroyuki
    Nosaka, Kazuto
    BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (21) : 9400 - 9408
  • [33] Crystallization of SARS Coronavirus 3CL Protease to Identify Inhibitor Targets
    Fernandes, Samantha Zinnia
    Anson, Brandon
    Mesecar, Andrew
    FASEB JOURNAL, 2019, 33
  • [34] Mechanism of the maturation process of SARS-CoV 3CL protease
    Hsu, MF
    Kuo, CJ
    Chang, KT
    Chang, HC
    Chou, CC
    Ko, TP
    Shr, HL
    Chang, GG
    Wang, AHJ
    Liang, PH
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (35) : 31257 - 31266
  • [35] Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure-activity relationship study
    Thanigaimalai, Pillaiyar
    Konno, Sho
    Yamamoto, Takehito
    Koiwai, Yuji
    Taguchi, Akihiro
    Takayama, Kentaro
    Yakushiji, Fumika
    Akaji, Kenichi
    Kiso, Yoshiaki
    Kawasaki, Yuko
    Chen, Shen-En
    Naser-Tavakolian, Aurash
    Schoen, Arne
    Freire, Ernesto
    Hayashi, Yoshio
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 65 : 436 - 447
  • [36] Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety
    Konno, Sho
    Thanigaimalai, Pillaiyar
    Yamamoto, Takehito
    Nakada, Kiyohiko
    Kakiuchi, Rie
    Takayama, Kentaro
    Yamazaki, Yuri
    Yakushiji, Fumika
    Akaji, Kenichi
    Kiso, Yoshiaki
    Kawasaki, Yuko
    Chen, Shen-En
    Freire, Ernesto
    Hayashi, Yoshio
    BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 21 (02) : 412 - 424
  • [37] Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening
    Zhu, Wei
    Xu, Miao
    Chen, Catherine Z.
    Guo, Hui
    Shen, Min
    Hu, Xin
    Shinn, Paul
    Klumpp-Thomas, Carleen
    Michael, Samuel G.
    Zheng, Wei
    ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2020, 3 (05) : 1008 - 1016
  • [38] Novel prodrugs of transition state inhibitors of norovirus 3CL protease
    Kankanamalage, Anushka Galasiti
    Kim, Yunjeong
    Alliston, Kevin
    Rathnayake, Athri
    Butler, Michelle
    Cardinale, Setven
    Bowlin, Terry
    Chang, Kyeong-Ok
    Groutas, William
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [39] Capillary electrokinetic chromatography for chiral separation of potential SARS-CoV-2 3CL protease inhibitors
    Brier, Lucile
    Furman, Christophe
    Charton, Julie
    Deprez, Benoit
    Lipka, Emmanuelle
    ELECTROPHORESIS, 2024, 45 (11-12) : 1010 - 1017
  • [40] The Interaction of Antiviral Drugs with SARS-Cov-2 3CL Protease
    Saadh, Mohamed J.
    JOURNAL OF PHARMACEUTICAL NEGATIVE RESULTS, 2022, 13 (03) : 865 - 868