Gold-Catalyzed Intermolecular Oxidation of Terminal Alkynes: Simple and Efficient Synthesis of α-Mesyloxy Ketones

被引：28

作者：

Xie, Longyong ^{[1
]}

Liang, Zhiwu ^{[1
]}

Yan, Dong ^{[1
,2
]}

He, Weimin ^{[1
]}

Xiang, Jiannan ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

[2] Hunan Chem Ind Vocat Technol Inst, Zhuzhou 412004, Peoples R China

来源：

SYNLETT | 2013年 / 24卷 / 14期

基金：

湖南省自然科学基金;

关键词：

alkynes; homogenous catalysis; gold; alpha-oxo gold carbine; alpha-mesyloxy ketones; ONE-POT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; PHOTOCHEMICAL-SYNTHESIS; REARRANGEMENT; HETEROCYCLES; YLIDES; ACCESS; ROUTE; CYCLOPROPANATION; CYCLOADDITION;

D O I：

10.1055/s-0033-1339337

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A variety of terminal alkynes were efficiently converted into the corresponding alpha-mesyloxy ketones through gold-catalyzed intermolecular oxidation in the presence of 3,5-dichloropyridine N-oxide as the oxidant. The reaction is proposed to proceed via alpha-oxo gold carbene intermolecular O-H insertion.

引用

页码：1809 / 1812

页数：4

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