Development of Ulcer Disease After Roux-en-Y Gastric Bypass, Incidence, Risk Factors, and Patient Presentation: A Systematic Review

被引：143

作者：

Coblijn, Usha K. ^{[1
]}

Goucham, Amin B. ^{[1
]}

Lagarde, Sjoerd M. ^{[1
]}

Kuiken, Sjoerd D. ^{[2
]}

van Wagensveld, Bart A. ^{[1
]}

机构：

[1] Sint Lucas Andreas Hosp, Dept Surg, NL-1061 Amsterdam, Netherlands

[2] Sint Lucas Andreas Hosp, Dept Gastroenterol, NL-1061 Amsterdam, Netherlands

来源：

OBESITY SURGERY | 2014年 / 24卷 / 02期

关键词：

Anastomotic ulcer; Bariatric surgery; Bleeding ulcer; Gastric bypass; Ischemic ulcer; Marginal ulcer; Morbid obesity; Perforation; Roux-en-Y gastric bypass; RYGB; Ulcer; HELICOBACTER-PYLORI INFECTION; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; PEPTIC-ULCER; MARGINAL ULCER; BARIATRIC SURGERY; CIRCULAR STAPLER; MEDICAL THERAPY; UNITED-STATES; STOMAL ULCER; HAND-SEWN;

D O I：

10.1007/s11695-013-1118-5

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Laparoscopic Roux-en-Y gastric bypass (LRYGB) is the gold standard in bariatric surgery. A long-term complication can be marginal ulceration (MU) at the gastrojejunostomy. The mechanism of development is unclear and symptoms vary. Management and prevention is a continuous subject of debate. The aim was to assess the incidence, mechanism, symptoms, and management of MU after LRYGB by means of a systematic review. Forty-one studies with a total of 16,987 patients were included, 787 (4.6 %) developed MU. The incidence of MU varied between 0.6 and 25 %. The position and size of the pouch, smoking, and nonsteroidal inflammatory drugs usage are associated with the formation of MU. In most cases, MU is adequately treated with proton pump inhibitors, sometimes reoperation is required. Laparoscopic approach is safe and effective.

引用

页码：299 / 309

页数：11

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