Patterns of antipsychotics' prescription in Portuguese acute psychiatric wards: A cross-sectional study

被引:13
作者
Mendes, Joao Campos [1 ]
Azeredo-Lopes, Sofia [2 ]
Cardoso, Graca [3 ]
机构
[1] Hosp Sousa Martins, Dept Psiquiatria & Saude Mental, Unidade Local Saude Guarda, Guarda, Portugal
[2] Univ Nova Lisboa, Dept Biostat & Informat, NOVA Med Sch, Fac Ciencias Med, Lisbon, Portugal
[3] Univ Nova Lisboa, Chron Dis Res Ctr CEDOC, NOVA Med Sch, Fac Ciencias Med, Lisbon, Portugal
关键词
Antipsychotics; Polypharmacy; High-doses; Psychiatric inpatient units; QUALITY-OF-CARE; HOSPITALIZED-PATIENTS; PRESCRIBING PATTERNS; SCHIZOPHRENIA; POLYPHARMACY; ARIPIPRAZOLE; GUIDELINES; INPATIENTS; ETHNICITY; BENEFITS;
D O I
10.1016/j.psychres.2016.09.035
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
This study aimed to establish the prescribing patterns of antipsychotics in acute psychiatric wards across Portugal, to determine the prevalence of polypharmacy and "high-doses" treatment, and to identify possible predictors. Twelve acute psychiatric inpatient units and 272 patients were included. The majority (87.5%) was treated with antipsychotics regardless of diagnosis, and 41.6% had at least two antipsychotics prescribed in combination. Age, use of depot antipsychotics, and antipsychotic "high doses" were significant predictors of antipsychotic polypharmacy. Excluding 'as required' prescriptions, 13.8% of the patients were prescribed "high-doses" of anti psychotics. When antipsychotics 'as required' prescriptions were considered, 49.2% of the patients were on antipsychotic "high-doses". Age, use of depot antipsychotics, previous psychiatric hospitalization and involuntary admission were significant predictors of antipsychotic "high-doses". These results show that in Portugal the antipsychotics prescribing practices in psychiatric inpatient units diverge from those that are universally recommended, entailing important clinical and economic implications. It seems advisable to optimize the prescription of these drugs, in order to prevent adverse effects and improve the quality of the services provided. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:142 / 148
页数:7
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