Syntheses, characterizations and bioactivities on HeLa cells and KB cells of two dinuclear manganese complexes with carboxylate bridges

被引：6
作者：
Gao, En-Jun [1 ]
Lin, Lin [1 ]
Wang, Bo [1 ]
Zhu, Ming-Chang [1 ]
Jiao, Wei [1 ]
Liu, Ting-Li [1 ]
机构：
[1] Shenyang Univ Chem Technol, Dept Coordinat Chem, Int Key Lab Shenyang Inorgan Mol Based Chem, Shenyang, Peoples R China
来源：
JOURNAL OF COORDINATION CHEMISTRY | 2013年 / 66卷 / 11期
关键词：
HeLa cells; KB cells; Manganese complexes; Gel electrophoresis; Cytotoxicity; Apoptosis; CYTOTOXICITY IN-VITRO; DNA-BINDING; CRYSTAL-STRUCTURE; COPPER(II) COMPLEXES; SPECTRAL PROPERTIES; CLEAVAGE; LIGANDS; PD(II); PT(II); ACID;
D O I：
10.1080/00958972.2013.786830
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
To explore anti-tumor activities of manganese complexes, two complexes have been synthesized and characterized. Complex 1 is bridged by 1,10-phenanthroline and 2,4-biphenyl dicarboxylate. The two complexes have strong fluorescent emission and interact with DNA in an intercalative mode. The complexes also exhibit significant cytotoxic specificity and cancer cell inhibition.
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收藏
页码：1945 / 1958
页数：14
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