Apoptosis of Human Gastric Cancer Cell Line SGC-7901 Induced by Allicin

被引：0
作者：
Shao Shu-Li [1 ]
Zhang Wei-Wei [1 ]
Li Feng-Ying [1 ]
机构：
[1] Qiqihar Univ, Coll Life Sci, Qiqihar 161006, Hei Longjiang P, Peoples R China
来源：
MATERIALS FOR ENVIRONMENTAL PROTECTION AND ENERGY APPLICATION, PTS 1 AND 2 | 2012年 / 343-344卷
关键词：
Allicin; apoptosis; gastric cancer cell line SGC-7901; MODE;
D O I：
10.4028/www.scientific.net/AMR.343-344.1285
中图分类号：
TE [石油、天然气工业]; TK [能源与动力工程];
学科分类号：
0807 ; 0820 ;
摘要：
To observe the effects of allicin on the growth and apoptosis of gastric cancer cell line. The viability of gastric cancer cell line SGC-7901 was determined by MTT, cell morphology was observed under AO staining and electron microscopy, the apoptosis was measured using flow cytometry analysis. The results indicated that the growth of gastric cancer cell line SGC-7901 was significantly inhibited by allicin, and the IC50 was 80 mu g/mL. Morphological variations of apoptosis were observed at 48 hours treated with allicin by AO staining and apoptosis body was observed under electron microscope. The results indicated that allicin can suppress the growth of gastric cancer cell line SGC-7901 and induce apoptosis of the cells.
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页码：1285 / 1289
页数：5
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