Physicochemical Characterization and Prospecting Biological Activity of Some Authentic Transylvanian Essential Oils: Lavender, Sage and Basil

被引：14
作者：
Varban, Dan [1 ]
Zahan, Marius [2 ]
Pop, Carmen Rodica [3 ]
Socaci, Sonia [3 ]
Stefan, Razvan [4 ,5 ]
Crisan, Ioana [1 ,6 ]
Bota, Loredana Elena [4 ]
Miclea, Ileana [2 ]
Musca, Adriana Sebastiana [2 ]
Deac, Alexandru Marius [2 ]
Varban, Rodica [1 ]
机构：
[1] Univ Agr Sci & Vet Med Cluj Napoca, Fac Agr, Calea Manastur St 3-5, Cluj Napoca 400372, Romania
[2] Univ Agr Sci & Vet Med Cluj Napoca, Fac Anim Sci & Biotechnol, Calea Manastur St 3-5, Cluj Napoca 400372, Romania
[3] Univ Agr Sci & Vet Med Cluj Napoca, Fac Food Sci & Technol, Calea Floresti 64, Cluj Napoca 400509, Romania
[4] Univ Agr Sci & Vet Med Cluj Napoca, Fac Vet Med, Calea Manastur St 3-5, Cluj Napoca 400372, Romania
[5] Univ Agr Sci & Vet Med Cluj Napoca, Life Sci Inst King Michael I Romania, Dept Biophys, Calea Manastur St 3-5, Cluj Napoca 400372, Romania
[6] Univ Agr Sci & Vet Med Cluj Napoca, Agrobot Garden CLA, Calea Manastur St 3-5, Cluj Napoca 400372, Romania
来源：
METABOLITES | 2022年 / 12卷 / 10期
关键词：
quality; volatile; cancer cell line; pathogenic bacteria; secondary metabolites; analysis; SALVIA-OFFICINALIS; LAVANDULA-ANGUSTIFOLIA; CHEMICAL-COMPOSITION; ANTIBACTERIAL ACTIVITY; GLANDULAR TRICHOMES; ANTICANCER ACTIVITY; IN-VITRO; L; PLANTS; IDENTIFICATION;
D O I：
10.3390/metabo12100962
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Essential oils are a category of agro-based industrial products experiencing increasing demand. In this research, three essential oils obtained by steam distillation from lavender, sage and basil plants cultivated in temperate continental conditions of Transylvania were investigated for chemical composition, physical characteristics and biological activity (antimicrobial and cytotoxic effect on cancer cell lines). The number of identified compounds varied: 38 for lavender, 29 for sage essential oil and 41 for basil. The volatile profile was dominated by terpenes and terpenoids (>80%). Major components were beta-linalool and linalool acetate in lavender essential oil; thujones and camphor in sage essential oil; beta-linalool, thujone, camphor and eucalyptol in basil essential oil. Refractive index of the essential oils was lowest for lavender and highest for sage. Antibacterial activity was strongest for basil, moderate for lavender and weakest for sage essential oil. The most active on both colon adenocarcinoma (Caco-2) and ovary carcinoma (A2780) was sage essential oil.
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页数：21
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