Chemical constituents from the leaves of Manglietia phuthoensis and their effects on osteoblastic MC3T3-E1 cells

被引：28

作者：

Van Kiem, Phan ^{[2
]}

Tri, Mai Dinh ^{[2
]}

Tuong, Le Vo Dinh ^{[2
]}

Tung, Nguyen Huu ^{[1
,2
]}

Hanh, Nguyen Ngoc ^{[3
]}

Quang, Tran Hong ^{[2
]}

Cuong, Nguyen Xuan ^{[2
]}

Van Minh, Chau ^{[2
]}

Choi, Eun-Mi ^{[1
]}

Kim, Young Ho ^{[1
]}

机构：

[1] Chungnam Natl Univ, Coll Pharm, Taejon 305764, South Korea

[2] Vietnamese Acad Sci & Technol, Inst Nat Prod, Hanoi, Vietnam

[3] Inst Chem Technol, Ho Chi Minh City, Vietnam

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2008年 / 56卷 / 09期

关键词：

Manglietia phuthoensis; manglieside A; manglieside B; manglieside C; manglieside D; manglieside E;

D O I：

10.1248/cpb.56.1270

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new phenyl glycosides, mangliesides A and B (1, 2), a new ionol glycoside, manglieside C (3), two new lignan glycosides, mangliesides D and E (4, 5), were isolated front the leaves of Manglietia phuthoensis, along with two known lignans, 3-methoxymagnolol (6) and obovatol (7). Their structures were established by means of 1D and 2D NMR, electrospray ionization (ESI)-MS and HR-ESI-MS experiments. Among them, compounds 2 and 5 significantly (p<0.05) increased the growth and differentiation of osteoblastic MC3T3-E1 cells in vitro.

引用

页码：1270 / 1275

页数：6

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