Microwave-assisted solvent-free heterocyclic synthesis

被引：176
|
作者：
Bougrin, K
Loupy, A
Soufiaoui, M
机构：
[1] Univ Mohammed V Agdal, Dept Chem, Lab Plants Chem & Organ & Bioorgan Synth, Fac Sci, Rabat, Morocco
[2] Paris S Univ, CNRS, UMR 8615, ICMMO,Lab Select React Supports, F-91405 Orsay, France
来源：
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS | 2005年 / 6卷 / 2-3期
关键词：
solvent-free reactions; microwave irradiation; heterocycles; 4+2] cycloaddition; 2+2] cycloaddition; 1,3-dipolar cycloaddition; cyclocondensation; combinatorial synthesis;
D O I：
10.1016/j.jphotochemrev.2005.07.001
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
In this review, we report the important role of solvent-free conditions coupled with microwave activation and their advantages in heterocyclic synthesis. This eco-friendly approach, which was found application in facile organic synthesis, is applied to the rapid assembly of heteroatom organic compounds via cycloaddition and cyclocondensation reactions. Combinatorial heterocyclic synthesis under solvent-free conditions is described having allowed to build a library of such heterocyclic compounds of pharmacological interest. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：139 / 167
页数：29
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