A Practical and General Diels-Alder Reaction of Pentafulvenes with Arynes

被引：52

作者：

Bhojgude, Sachin Suresh ^{[1
]}

Kaicharla, Trinadh ^{[1
]}

Bhunia, Anup ^{[1
]}

Biju, Akkattu T. ^{[1
]}

机构：

[1] CSIR NCL, Div Organ Chem, Pune 411008, Maharashtra, India

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 16期

关键词：

1,3-DIPOLAR CYCLOADDITION; ORGANIC-SYNTHESIS; CARBON-CARBON; SIGMA-BONDS; FULVENES; CHEMISTRY; BENZYNE; DERIVATIVES; EFFICIENT; BENZONORBORNADIENES;

D O I：

10.1021/ol301742k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A high-yielding, versatile and practical Diels-Alder reaction of pentafulvenes with arynes under mild reaction conditions is reported. The aryne generated by the fluoride induced 1,2-elimination of 2-(trimethylsilyl)aryl triflates undergoes efficient cycloaddition with 6-substituted and 6,6-disubstituted pentafulvenes leading to the formation of benzonorbornadiene derivatives.

引用

页码：4098 / 4101

页数：4

共 51 条

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