Adsorption of chitosan on PET films monitored by quartz crystal microbalance

被引:29
作者
Indest, Tea [1 ]
Laine, Janne [2 ]
Ribitsch, Volker [3 ]
Johansson, Leena-Sisko [2 ]
Stana-Kleinschek, Karin [1 ]
Strnad, Simona [1 ]
机构
[1] Univ Maribor, Fac Mech Engn, Lab Characterizat & Proc Polymers, SI-2000 Maribor, Slovenia
[2] Aalto Univ, Lab Forest Prod Chem, FI-02015 Espoo, Finland
[3] Karl Franzens Univ Graz, Inst Chem Rheol & Colloid Sci, A-8010 Graz, Austria
关键词
D O I
10.1021/bm800333p
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The adsorption behavior of chitosan on poly(ethylene terephthalate) (PET) model film surface was studied using the quartz crystal microbalance (QCM) technique. QCM with a dissipation unit (QCM-D) represents a very sensitive technique for adsorption studies at the solid/liquid interface in situ, with capability of detecting a submonolayer of adsorbate on the quartz crystal surface. Chitosan as well as PET were chosen for this study due to their promising biocompatible properties and numerous possibilities to be used in biomedical applications. As a first step, PET foils were activated by alkaline hydrolysis in order to increase their hydrophilicity. Model thin films were prepared from PET foils by the spin coating technique. The chemical composition of the obtained model PET films was analyzed using X-ray photoelectron spectroscopy (XPS) and their morphology was characterized by atomic force microscopy (AFM). Furthermore, the adsorption behavior of chitosan on these activated PET films and the influence of adsorption parameters (pH, ionic strength and chitosan solution concentration) were investigated in detail. Additionally, the surface chemistry and morphology of the PET films and the chitosan coated PET films were analyzed with XPS and AFM.
引用
收藏
页码:2207 / 2214
页数:8
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