Cost-effective lactic acid production by fermentation of agro-industrial residues

被引：28

作者：

Carpinelli Macedo, Joao Victor ^{[1
,4
]}

de Barros Ranke, Fabiane Fernanda ^{[1
]}

Escaramboni, Bruna ^{[1
]}

Campioni, Tania Sila ^{[1
,2
]}

Fernandez Nunez, Eutimio Gustavo ^{[3
]}

de Oliva Neto, Pedro ^{[1
]}

机构：

[1] Univ Estadual Paulista UNESP, Inst Pesquisa Bionergia, Lab Associado IPBEN, Unidade Bioproc, Av Dom Antonio 2100, BR-19806380 Assis, SP, Brazil

[2] Univ Fed Parana UFPR, Dept Engn & Exatas, Setor Palotina, Rua Pioneiro 2153, Palotina, Parana, Brazil

[3] Univ Sao Paulo, Escola Artes Ciencias & Humanidades, Rua Arlindo Bettio 1000, BR-03828000 Sao Paulo, SP, Brazil

[4] Univ Estadual Paulista UNESP, Lab Cent IPBEN, Inst Pesquisa Bioenergia, Rua 10,2527, BR-13500230 Rio Claro, SP, Brazil

来源：

BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY | 2020年 / 27卷

基金：

巴西圣保罗研究基金会;

关键词：

Lactic acid; Lactobacillus; Agro-industrial residues; Bioprocess; Fermentation; Biological treatment; CORN STEEP LIQUOR; CASSAVA;

D O I：

10.1016/j.bcab.2020.101706

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The substrate cost is a hurdle in the lactic acid (LA) manufacturing by microbial fermentations. Thus, this work aimed to optimize the production of LA by Lactobacillus amylovorus and Lactobacillus acidophilus in a culture medium containing agro-industrial wastes, cassava bagasse (CB, 6-18%, w/v) and corn steep liquor (CSL, 4-12%, v/v). Initially, the optimal medium composition was defined; different fermentation times were also assessed. CB was used in natura or hydrolyzed by Rhizopus oligosporus' amylase. In a batch process without pH control, the LA maximum concentration (31.6 g/L-h) and productivity (0.11 A) were obtained by L. amylovorus using 14% (w/v) hydrolyzed CB and 10% (v/v) CSL. However, when a Fed-batch process was performed with pH control and using the optimized culture medium composition, high volumetric productivity (0.46 g/L-h) was achieved. The optimized medium's cost is 0.05 US$/L. These findings suggest a promising bioprocess for LA manufacturing from agro-industrial wastes.

引用

页数：9

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