Carboxylation of dihydroxoplatinum(IV) complexes via a new synthetic pathway

被引：67

作者：

Galanski, M ^{[1
]}

Keppler, BK ^{[1
]}

机构：

[1] UNIV HEIDELBERG,INST ANORGAN CHEM,D-69120 HEIDELBERG,GERMANY

来源：

INORGANIC CHEMISTRY | 1996年 / 35卷 / 06期

关键词：

D O I：

10.1021/ic9509490

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The carboxylation of dihydroxoplatinum(IV) compounds by acyl chlorides is described. This new reaction in synthetic inorganic chemistry is ideally suited to the synthesis of a wide variety of new potential representatives of orally administrable bis(carboxylato)platinum(IV) complexes which would be difficult to prepare by substitution reactions.

引用

页码：1709 / &

页数：4

共 15 条

[1]

Dhara S.C., 1970, INDIAN J CHEM, V8, P193

[2] The behaviour of chelate groupings attached to platinum and to palladium [J].

Drew, HDK .

JOURNAL OF THE CHEMICAL SOCIETY, 1932, :2328-2331

[3] CRYSTALLINE-STRUCTURE AND VIBRATIONAL-SPECTRA OF CIS-DICHLORODIAMMINE-TRANS-DIHYDROXO-PLATINUM(IV), PTCL2(NH3)2(OH)2 [J].

FAGGIANI, R ;

HOWARDLOCK, HE ;

LOCK, CJL ;

LIPPERT, B ;

ROSENBERG, B .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1982, 60 (04) :529-534

[4] CARBOXYLATION OF KINETICALLY INERT PLATINUM(IV) HYDROXY COMPLEXES - AN ENTREE INTO ORALLY-ACTIVE PLATINUM(IV) ANTITUMOR AGENTS [J].

GIANDOMENICO, CM ;

ABRAMS, MJ ;

MURRER, BA ;

VOLLANO, JF ;

RHEINHEIMER, MI ;

WYER, SB ;

BOSSARD, GE ;

HIGGINS, JD .

INORGANIC CHEMISTRY, 1995, 34 (05) :1015-1021

[5]

JUDSON I, 1995, 7 INT S PLAT OTH MET

[6] NEW PLATINUM ANTITUMOR COMPLEXES [J].

KELLAND, LR .

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 1993, 15 (03) :191-219

[7]

KELLAND LR, 1992, PLATIN MET REV, V36, P178

[8] SYNTHESIS AND ANTITUMOR-ACTIVITY OF AMMINE AMINE PLATINUM(II) AND PLATINUM(IV) COMPLEXES [J].

KHOKHAR, AR ;

DENG, YJ ;

ALBAKER, S ;

YOSHIDA, M ;

SIDDIK, ZH .

JOURNAL OF INORGANIC BIOCHEMISTRY, 1993, 51 (03) :677-687

[9] PREPARATION, CHARACTERIZATION, AND ANTITUMOR-ACTIVITY OF NEW ETHYLENEDIAMINE PLATINUM(IV) COMPLEXES CONTAINING MIXED CARBOXYLATE LIGANDS [J].

KHOKHAR, AR ;

DENG, YJ ;

KIDO, Y ;

SIDDIK, ZH .

JOURNAL OF INORGANIC BIOCHEMISTRY, 1993, 50 (02) :79-87

[10] CRYSTAL AND MOLECULAR-STRUCTURE OF 3 ISOMERS OF DICHLORODIAMMINEDIHYDROXOPLATINUM(IV) - CIS-TRANS ISOMERIZATION ON RECRYSTALLIZATION FROM WATER [J].

KURODA, R ;

NEIDLE, S ;

ISMAIL, IM ;

SADLER, PJ .

INORGANIC CHEMISTRY, 1983, 22 (24) :3620-3624

← 1 2 →