Updates on the association of brain injury and Alzheimer's disease

被引:12
作者
Klomparens, Kara [1 ]
Ding, Yuchuan [1 ,2 ]
机构
[1] Wayne State Univ, Sch Med, Dept Neurosurg, Detroit, MI 48202 USA
[2] John D Dingell VA Med Ctr, 4646 John R St 11R, Detroit, MI 48201 USA
关键词
Age of onset; genetic predisposition; head trauma; neurodegenerative disease; severity; HEAD TRAUMA; RISK-FACTORS; DEMENTIA; PROTEINS; AD;
D O I
10.4103/bc.bc_18_20
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The purpose of this minireview is to outline the updates made on the association of Alzheimer's disease (AD) and brain injury. A review of the literature on this subject was conducted that included various aspects such as age of onset, severity of head trauma, and genetic influences. The results of this mini-review were that consistent associations of AD risk are seen when the severity of head trauma increases, the lag time decreases and when genetic links are present. Brain injury and AD have a complicated relationship that requires further studies to be fully understood.
引用
收藏
页码:65 / 69
页数:5
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