Prebiotics, gut microbiota and metabolic risks: Unveiling the relationship

被引:37
|
作者
Yasmin, Adeela [1 ]
Butt, Masood Sadiq [2 ]
Afzaal, Muhammad [1 ]
van Baak, Marleen [3 ]
Nadeem, Muhammad Tahir [1 ]
Shahid, Muhammad Zia [1 ]
机构
[1] Govt Coll Univ, Dept Food Sci, Faisalabad, Pakistan
[2] Univ Agr Faisalabad, Natl Inst Food Sci & Technol, Faisalabad, Pakistan
[3] Maastricht Univ, Fac Hlth Med & Life Sci, Dept Human Biol, Maastricht, Netherlands
关键词
Metabolic disorders; Prebiotics; Gut microbes; Bifidobacteria; Hypercholesterolaemia; Hyperglycaemia; CHAIN FRUCTO-OLIGOSACCHARIDES; FATTY-ACID CONCENTRATIONS; HUMAN COLONIC MICROBIOTA; INTESTINAL MICROBIOTA; FECAL BIFIDOBACTERIA; INSULIN SENSITIVITY; DIETARY MODULATION; HEPATIC STEATOSIS; FUNCTIONAL FOODS; RESISTANT STARCH;
D O I
10.1016/j.jff.2015.05.004
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The human gastrointestinal tract is colonized by trillions of microbes comprising thousands of bacterial phylotypes. Recent metagenomic studies of the human gut microbiota have revealed the presence of millions of genes, as compared to genes present in the entire human body. Perturbation in the level of gut microorganisms may lead to the onset of metabolic disorders. However, compelling evidence has also suggested that a particular gut microbial community may halt the occurrence of metabolic risk factors. Restoration of the beneficial gut microbial balance is difficult to achieve but the exploitation of prebiotics has led to promising outcomes in various studies. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:189 / 201
页数:13
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