Germline MC1R variants and BRAF mutant melanoma

被引：9

作者：

Hacker, Elke ^{[1
]}

Hayward, Nicholas K. ^{[1
]}

机构：

[1] Queensland Inst Med Res, Oncogen Lab, Brisbane, Qld 4006, Australia

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2008年 / 128卷 / 10期

关键词：

D O I：

10.1038/jid.2008.236

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. This finding provides insight into the relationship between host genotype and selection for somatic mutation type. Additional larger studies are required in diverse populations to further examine the interaction between MC1R and BRAF in different melanoma subtypes.

引用

页码：2354 / 2356

页数：4

共 50 条

[31] MC1R variants as genetic markers of increased risk of melanoma in persons with protective phenotype [J].

Kanetsky, Peter ;

Panossian, Saarene ;

Elder, David ;

Guerry, DuPont ;

Ming, Michael ;

Schuchter, Lynn ;

Rebbeck, Timothy .

CANCER RESEARCH, 2009, 69

[32] Localisation of the melanocortin 1 receptor (MC1R) within melanoma cells suggests that MC1R is present at the melanosome [J].

Jackson, C ;

Robinson, S ;

Healy, E .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2004, 123 (02)

[33] MC1R gene variants and sporadic malignant melanoma susceptibility in the Canary Islands population [J].

Cordoba-Lanus, Elizabeth ;

Hernandez-Jimenez, Jose G. ;

Medina-Coello, Chaxiraxi ;

Espinoza-Jimenez, Adriana ;

Gonzalez, Ana ;

Rodriguez-Perez, Maria-del-Cristo ;

Carretero-Hernandez, Gregorio ;

Almeida, Pablo ;

Suarez-Hernandez, Jose ;

Perera-Molinero, Antonio ;

Fernandez-de-Misa, Ricardo .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 2014, 306 (01) :51-58

[34] MC1R variants increase melanoma risk independent from previous ultraviolet radiation [J].

Wendt, J. ;

Rauscher, S. ;

Burgstaller-Muehlbacher, S. ;

Fae, I. ;

Fischer, G. ;

Pehamberger, H. ;

Okamoto, I. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2013, 133 :S233-S233

[35] MC1R variants predisposing to concomitant primary cutaneous melanoma in a monozygotic twin pair [J].

Pellegrini, Cristina ;

Fargnoli, Maria Concetta ;

Suppa, Mariano ;

Peris, Ketty .

BMC MEDICAL GENETICS, 2012, 13

[36] Common genetic variants associated with melanoma risk or naevus count in patients with wildtype MC1R melanoma [J].

Calbet-Llopart, Neus ;

Combalia, Marc ;

Kiroglu, Anil ;

Potrony, Miriam ;

Tell-Marti, Gemma ;

Combalia, Andrea ;

Brugues, Albert ;

Podlipnik, Sebastian ;

Carrera, Cristina ;

Puig, Susana ;

Malvehy, Josep ;

Puig-Butille, Joan Anton .

BRITISH JOURNAL OF DERMATOLOGY, 2022, 187 (05) :753-764

[37] Contribution of MC1R Genotype and Novel Common Genomic Variants to Melanoma Risk Prediction [J].

Cust, A. E. ;

Bui, M. ;

Goumas, C. ;

Jenkins, M. A. .

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2014, 23 (03) :566-567

[38] MC1R variants, melanoma and red hair color phenotype: A meta-analysis [J].

Raimondi, Sara ;

Sera, Francesco ;

Gandini, Sara ;

Iodice, Simona ;

Caini, Saverio ;

Maisonneuve, Patrick ;

Fargnoli, Maria Concetta .

INTERNATIONAL JOURNAL OF CANCER, 2008, 122 (12) :2753-2760

[39] MC1R gene variants and sporadic malignant melanoma susceptibility in the Canary Islands population [J].

Elizabeth Córdoba-Lanús ;

José G. Hernández-Jiménez ;

Chaxiraxi Medina-Coello ;

Adriana Espinoza-Jiménez ;

Ana González ;

María-del-Cristo Rodríguez-Pérez ;

Gregorio Carretero-Hernández ;

Pablo Almeida ;

José Suárez-Hernández ;

Antonio Perera-Molinero ;

Ricardo Fernández-de-Misa .

Archives of Dermatological Research, 2014, 306 :51-58

[40] Inherited variants in the MC1R gene and survival from cutaneous melanoma: a BioGenoMEL study [J].

Davies, John R. ;

Randerson-Moor, Juliette ;

Kukalizch, Kairen ;

Harland, Mark ;

Kumar, Rajiv ;

Madhusudan, Srinivasan ;

Nagore, Eduardo ;

Hansson, Johan ;

Hoiom, Veronica ;

Ghiorzo, Paola ;

Gruis, Nelleke A. ;

Kanetsky, Peter A. ;

Wendt, Judith ;

Pjanova, Dace ;

Puig, Susana ;

Saiag, Philippe ;

Schadendorf, Dirk ;

Soufir, Nadem ;

Okamoto, Ichiro ;

Affleck, Paul ;

Garcia-Casado, Zaida ;

Ogbah, Zighereda ;

Ozola, Aija ;

Queirolo, Paola ;

Sucker, Antje ;

Barrett, Jennifer H. ;

van Doorn, Remco ;

Bishop, D. Timothy ;

Newton-Bishop, Julia .

PIGMENT CELL & MELANOMA RESEARCH, 2012, 25 (03) :384-394

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