Germline MC1R variants and BRAF mutant melanoma

被引：9

作者：

Hacker, Elke ^{[1
]}

Hayward, Nicholas K. ^{[1
]}

机构：

[1] Queensland Inst Med Res, Oncogen Lab, Brisbane, Qld 4006, Australia

来源：

JOURNAL OF INVESTIGATIVE DERMATOLOGY | 2008年 / 128卷 / 10期

关键词：

D O I：

10.1038/jid.2008.236

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Recent studies have demonstrated that melanocortin-1 receptor (MC1R) variants increase the risk of melanomas harboring BRAF mutations. This finding provides insight into the relationship between host genotype and selection for somatic mutation type. Additional larger studies are required in diverse populations to further examine the interaction between MC1R and BRAF in different melanoma subtypes.

引用

页码：2354 / 2356

页数：4

共 50 条

[21] MC1R variants and cutaneous melanoma risk in the Southern Brazil population [J].

Do Nascimento, C. R. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2018, 138 (09) :B2-B2

[22] Melanoma disparity in Hawaii: Germline alterations of MC1R in a non-Caucasian population [J].

Morita, Shane Young ;

Lum, Christopher A. .

JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)

[23] Inherited MC1R variants in patients with melanoma are associated with better survival in women [J].

Lira, F. E. ;

Podlipnik, S. ;

Potrony, M. ;

Tell-Marti, G. ;

Calbet-Llopart, N. ;

Barreiro, A. ;

Carrera, C. ;

Malvehy, J. ;

Puig, S. .

BRITISH JOURNAL OF DERMATOLOGY, 2020, 182 (01) :138-146

[24] MC1R variants and melanoma risk: First study on Melan-Cohort [J].

Soufir, N. ;

Miss, L. Bagait ;

Miss, C. Oudin ;

Wolkenstein, P. ;

Descamps, V. ;

Dupin, N. ;

Lebbe, C. ;

Basset-Seguin, N. ;

Saiag, P. ;

Grandchamp, B. .

JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (18)

[25] Melanoma risk associated with MC1R gene variants in Latvia and the functional analysis of rare variants [J].

Ozola, Aija ;

Azarjana, Kristine ;

Donina, Simona ;

Proboka, Guna ;

Mandrika, Ilona ;

Petrovska, Ramona ;

Cema, Ingrida ;

Heisele, Olita ;

Engele, Ludmila ;

Streinerte, Baiba ;

Pjanova, Dace .

CANCER GENETICS, 2013, 206 (03) :81-91

[26] Associations of phenotypic characteristics, MC1R variants, and prior amelanotic melanoma with incident amelanotic melanoma [J].

Vernali, S. ;

Kanetsky, P. A. ;

Orlow, I. ;

Luo, L. ;

Berwick, M. ;

Thomas, N. E. .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (05) :S28-S28

[27] MC1R CpG island regulates MC1R expression and is methylated in a subset of melanoma tumours [J].

Budden, Timothy ;

Bowden, Nikola A. .

PIGMENT CELL & MELANOMA RESEARCH, 2019, 32 (02) :320-325

[28] Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors [J].

Guida, Michele ;

Strippoli, Sabino ;

Ferretta, Anna ;

Bartolomeo, Nicola ;

Porcelli, Letizia ;

Maida, Immacolata ;

Azzariti, Amalia ;

Tommasi, Stefania ;

Grieco, Claudia ;

Guida, Stefania ;

Albano, Anna ;

Lorusso, Vito ;

Guida, Gabriella .

PIGMENT CELL & MELANOMA RESEARCH, 2016, 29 (06) :679-687

[29] GSTP1 and MC1R in melanoma susceptibility [J].

Sturm, R. A. .

BRITISH JOURNAL OF DERMATOLOGY, 2012, 166 (06) :1155-1156

[30] MC1R variants in childhood and adolescent melanoma: a retrospective pooled analysis of a multicentre cohort [J].

Pellegrini, Cristina ;

Botta, Francesca ;

Massi, Daniela ;

Martorelli, Claudia ;

Facchetti, Fabio ;

Gandini, Sara ;

Maisonneuve, Patrick ;

Avril, Marie-Francoise ;

Demenais, Florence ;

Bressac-de Paillerets, Brigitte ;

Hoiom, Veronica ;

Cust, Anne E. ;

Anton-Culver, Hoda ;

Gruber, Stephen B. ;

Gallagher, Richard P. ;

Marrett, Loraine ;

Zanetti, Roberto ;

Dwyer, Terence ;

Thomas, Nancy E. ;

Begg, Colin B. ;

Berwick, Marianne ;

Puig, Susana ;

Potrony, Miriam ;

Nagore, Eduardo ;

Ghiorzo, Paola ;

Menin, Chiara ;

Manganoni, Ausilia Maria ;

Rodolfo, Monica ;

Brugnara, Sonia ;

Passoni, Emanuela ;

Sekulovic, Lidija Kandolf ;

Baldini, Federica ;

Guida, Gabriella ;

Stratigos, Alexandros ;

Ozdemir, Fezal ;

Ayala, Fabrizio ;

Fernandez-de-Misa, Ricardo ;

Quaglino, Pietro ;

Ribas, Gloria ;

Romanini, Antonella ;

Migliano, Emilia ;

Stanganelli, Ignazio ;

Kanetsky, Peter A. ;

Antonietta Pizzichetta, Maria ;

Garcia-Borron, Jose Carlos ;

Nan, Hongmei ;

Landi, Maria Teresa ;

Little, Julian ;

Newton-Bishop, Julia ;

Sera, Francesco .

LANCET CHILD & ADOLESCENT HEALTH, 2019, 3 (05) :332-342

← 1 2 3 4 5 →