The role of the sinusoidal endothelium in liver function

被引：49

作者：

Reichen, J ^{[1
]}

机构：

[1] Univ Bern, Dept Clin Pharmacol, CH-3010 Bern, Switzerland

来源：

NEWS IN PHYSIOLOGICAL SCIENCES | 1999年 / 14卷

关键词：

D O I：

10.1152/physiologyonline.1999.14.3.117

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Microvascular exchange in the liver is governed by fenestrations in sinusoidal endothelial cells and can be manipulated pharmacologically. Microvascular exchange is affected in alcoholic liver disease and cirrhosis, the former leading to a loss of fenestrae, the latter to sinusoidal capillarization and thereby to loss of liver function in disease.

引用

页码：117 / 121

页数：5

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