Water Soluble Polymers for Pharmaceutical Applications

被引：434
作者：
Kadajji, Veeran Gowda [1 ]
Betageri, Guru V. [1 ]
机构：
[1] Western Univ Hlth Sci, Dept Pharmaceut Sci, Pomona, CA 91766 USA
来源：
POLYMERS | 2011年 / 3卷 / 04期
关键词：
polymers; natural; synthetic; hydrogels; gums; cellulose ethers; povidone; polyethylene glycol; polyacrylamides; polyacrylic acid copolymers;
D O I：
10.3390/polym3041972
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Advances in polymer science have led to the development of novel drug delivery systems. Some polymers are obtained from natural resources and then chemically modified for various applications, while others are chemically synthesized and used. A large number of natural and synthetic polymers are available. In the present paper, only water soluble polymers are described. They have been explained in two categories (1) synthetic and (2) natural. Drug polymer conjugates, block copolymers, hydrogels and other water soluble drug polymer complexes have also been explained. The general properties and applications of different water soluble polymers in the formulation of different dosage forms, novel delivery systems and biomedical applications will be discussed.
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收藏
页码：1972 / 2009
页数：38
相关论文
共 234 条
[41]   POLYACRYLAMIDE GEL ELECTROPHORESIS [J].
CHRAMBACH, A ;
RODBARD, D .
SCIENCE, 1971, 172 (3982) :440-+
[42]   Determination of viscoelastic and rheo-optical material functions of water-soluble cellulose derivatives [J].
Clasen, C ;
Kulicke, WM .
PROGRESS IN POLYMER SCIENCE, 2001, 26 (09) :1839-1919
[43]   AN INVESTIGATION INTO THE STRUCTURE AND PROPERTIES OF CARBOPOL-934 GELS USING DIELECTRIC-SPECTROSCOPY AND OSCILLATORY RHEOMETRY [J].
CRAIG, DQM ;
TAMBURIC, S ;
BUCKTON, G ;
NEWTON, JM .
JOURNAL OF CONTROLLED RELEASE, 1994, 30 (03) :213-223
[44]  
Damascelli B, 2001, CANCER, V92, P2592, DOI 10.1002/1097-0142(20011115)92:10<2592::AID-CNCR1612>3.0.CO
[45]  
2-4
[46]   CONTROL OF DIABETES WITH POLYACRYLAMIDE IMPLANTS CONTAINING INSULIN [J].
DAVIS, BK .
EXPERIENTIA, 1972, 28 (03) :348-&
[47]   Biodegradable hydrogels based on stereocomplex formation between lactic acid oligomers grafted to dextran [J].
de Jong, SJ ;
De Smedt, SC ;
Demeester, J ;
van Nostrum, CF ;
Kettenes-van den Bosch, JJ ;
Hennink, WE .
JOURNAL OF CONTROLLED RELEASE, 2001, 72 (1-3) :47-56
[48]   Nanoparticles as protein and gene carriers to mucosal surfaces [J].
de la Fuente, Maria ;
Csaba, Noemi ;
Garcia-Fuentes, Marcos ;
Alonso, Maria Jose .
NANOMEDICINE, 2008, 3 (06) :845-857
[49]   Cationic polymer based gene delivery systems [J].
De Smedt, SC ;
Demeester, J ;
Hennink, WE .
PHARMACEUTICAL RESEARCH, 2000, 17 (02) :113-126
[50]   LYSOSOMOTROPIC AGENTS [J].
DEDUVE, C ;
DEBARSY, T ;
POOLE, B ;
TROUET, A ;
TULKENS, P ;
VANHOOF, F .
BIOCHEMICAL PHARMACOLOGY, 1974, 23 (18) :2495-+
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