Thymoma and radiation therapy: a systematic review of medical treatment

被引：0
|
作者：
Giannopoulou, Alexandra [1 ]
Gkiozos, Ioannis [2 ]
Harrington, Kevin J. [3 ]
Syrigos, Konstantinos N. [2 ,4 ]
机构：
[1] Attikon Univ Gen Hosp, Dept Radiat Therapy, Athens, Greece
[2] Athens Med Sch GR, Sotiria Gen Hosp, Oncol Unit GPP, Athens 11527, Greece
[3] Inst Canc Res, London SW3 6JB, England
[4] Yale Univ, Sch Med, New Haven, CT USA
来源：
EXPERT REVIEW OF ANTICANCER THERAPY | 2013年 / 13卷 / 06期
关键词：
chemotherapy; radiation therapy; surgery; thymoma; thymus malignancies; THYMIC EPITHELIAL TUMORS; POSTOPERATIVE RADIOTHERAPY; CLINICOPATHOLOGICAL FEATURES; SURGICAL RESECTION; PROGNOSTIC-FACTORS; INVASIVE THYMOMA; PHASE-II; CHEMOTHERAPY; RECURRENCE; CARCINOMA;
D O I：
10.1586/ERA.13.54
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Thymoma is the most common tumor in the anterior mediastinum (50% in adults). This review presents an update of thymoma treatment, commonly based on the Masaoka clinical staging system. The best treatment option is complete resection with no adjuvant approach in early stages and complete response. For incomplete resection, postoperative radiotherapy is recommended (5-year survival: 50-60%). For unresectable disease, concurrent chemoradiotherapy is performed. In conclusion, high technology (3D radiotherapy, 4D radiotherapy, intensity-modulated radiotherapy, image-guided radiotherapy and computed tomography fusion with PET scan) optimizes tumor target definition and provides dose escalation.
引用
收藏
页码：759 / 766
页数：8
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