PHARMACODYNAMIC/PHARMACOKINETIC ASSESSMENT OF BEMIPARIN AFTER MULTIPLE PROPHYLACTIC AND SINGLE THERAPEUTIC DOSES IN YOUNG AND ELDERLY HEALTHY VOLUNTEERS AND IN SUBJECTS WITH VARYING DEGREES OF RENAL IMPAIRMENT

被引：0
|
作者：
Ayani, I [1 ]
Rico, R. [2 ,3 ]
Gich, I [2 ,3 ]
Ballester, M. R. [2 ,3 ]
Gutierro, I [4 ]
Borrelle, M. [5 ]
Martinez-Gonzalez, J. [1 ]
Fontcuberta, J. [5 ]
Antonijoan, R. M. [2 ,3 ,6 ]
机构：
[1] Labs Farmaceut Rovi SA, Med Dpt, Madrid, Spain
[2] CIM St Pau Inst Biomed Res, Barcelona, Spain
[3] Autonomous Univ Barcelona, E-08193 Barcelona, Spain
[4] Labs Farmaceut Rovi SA, R&D Dpt, Granada, Spain
[5] Hosp Santa Creu St Pau, Hemostasis & Thrombosis Unit, Barcelona, Spain
[6] Hosp Santa Creu St Pau, Clin Pharmacol Dept, Barcelona, Spain
来源：
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY | 2013年 / 113卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：14 / 14
页数：1
相关论文
共 50 条
  • [1] Pharmacodynamics assessment of Bemiparin after multiple prophylactic and single therapeutic doses in adult and elderly healthy volunteers and in subjects with varying degrees of renal impairment
    Rico, Salvador
    Antonijoan, Rosa-Maria
    Ballester, Maria Rosa
    Gutierro, Ibon
    Ayani, Ignacio
    Martinez-Gonzalez, Javier
    Borrell, Montserrat
    Fontcuberta, Jordi
    Gich, Ignasi
    THROMBOSIS RESEARCH, 2014, 133 (06) : 1029 - 1038
  • [2] Pharmacokinetics and safety of bemiparin after multiple prophylactic and single therapeutic doses in young and elderly healthy volunteers - no need for dose adjustment
    Rico, S.
    Antonijoan, R. M.
    Martinez-Colomer, J.
    Borrell, M.
    Fontcuberta, J.
    Monreal, M.
    Martinez-Gonzalez, J.
    Barbanoj, M. J.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 : 765 - 765
  • [3] Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after single and multiple doses in healthy volunteers
    Ramakrishnan, R
    Cheung, WK
    Wacholtz, MC
    Minton, N
    Jusko, WJ
    JOURNAL OF CLINICAL PHARMACOLOGY, 2004, 44 (09): : 991 - 1002
  • [4] ASSESSMENT OF BLEEDING RISK IN ELDERLY AND PATIENTS WITH RENAL IMPAIRMENT UNDER BEMIPARIN PROPHYLACTIC DOSES FOR MORE THAN 3 WEEKS
    Martinez-Gonzalez, J.
    Ayani, I.
    THROMBOSIS RESEARCH, 2016, 141 : S6 - S6
  • [5] Pharmacokinetics of repaglinide after single and multiple doses in patients with renal impairment compared with normal healthy volunteers
    Marbury, TC
    Hatorp, V
    DIABETES, 1998, 47 : A357 - A357
  • [6] Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after multiple subcutaneous doses in healthy subjects
    Krzyzanski, W
    Jusko, WJ
    Wacholtz, MC
    Minton, N
    Cheung, WK
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2005, 26 (3-4) : 295 - 306
  • [7] Safety, Pharmacokinetic, and Pharmacodynamic Evaluation After Single and Multiple Ascending Doses of a Novel Selective Androgen Receptor Modulator in Healthy Subjects
    Bhattacharya, Indranil
    Tarabar, Sanela
    Liang, Yali
    Pradhan, Vivek
    Owens, Jane
    Oemar, Barry
    CLINICAL THERAPEUTICS, 2016, 38 (06) : 1401 - 1416
  • [8] Pharmacodynamic and Pharmacokinetic Equivalences of Epoetin Hospira and Epogen After Multiple Subcutaneous Doses to Healthy Male Subjects
    Stalker, Dennis
    Ramaiya, Atulkumar
    Kumbhat, Seema
    Zhang, Jeffrey
    Reid, Susan
    Martin, Nancy
    CLINICAL THERAPEUTICS, 2016, 38 (05) : 1090 - 1101
  • [9] PHARMACOKINETIC AND PHARMACODYNAMIC STUDIES OF FELODIPINE IN HEALTHY-SUBJECTS AFTER VARIOUS SINGLE, ORAL AND INTRAVENOUS DOSES
    EDGAR, B
    REGARDH, CG
    LUNDBORG, P
    ROMARE, S
    NYBERG, G
    RONN, O
    BIOPHARMACEUTICS & DRUG DISPOSITION, 1987, 8 (03) : 235 - 248
  • [10] Pharmacokinetic and Pharmacodynamic Equivalence of Epoetin Hospira and Epogen After Single Subcutaneous Doses to Healthy Male Subjects
    Stalker, Dennis
    Reid, Susan
    Ramaiya, Atulkumar
    Wisemandle, Wayne A.
    Martin, Nancy E.
    CLINICAL THERAPEUTICS, 2016, 38 (08) : 1778 - 1788
12345