An efficient synthesis of 1α,25-dihydroxy-20-epi-vitamin D3

被引：7

作者：

Fraga, R. ^{[1
]}

Lopez-Perez, B. ^{[1
]}

Sokolowska, K. ^{[1
]}

Guini, A. ^{[1
]}

Regueira, T. ^{[1
]}

Diaz, S. ^{[1
]}

Mourino, A. ^{[1
]}

Maestro, M. A. ^{[2
]}

机构：

[1] Univ Santiago de Compostela, Dept Quim Organ, E-15782 Santiago De Compostela, Spain

[2] Univ A Coruna, Dept Quim Fundamental, E-15071 La Coruna, Spain

来源：

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY | 2013年 / 136卷

关键词：

Vitamin D analogues synthesis; 1; alpha; 25-Dihydroxy-20-epi-vitamin D-3; MC1288; Palladium(0)-catalyzed coupling; VITAMIN-D; ANALOGS; REGULATORS;

D O I：

10.1016/j.jsbmb.2013.01.010

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of 1 alpha,25-dihydroxy-20-epi-vitamin D-3 (1) by Pd(0)-catalyzed coupling between the boronate ester (2) and the enol triflate (3) is described. This article is part of a Special Issue entitled 'Vitamin D Workshop'. (c) 2013 Elsevier Ltd. All rights reserved.

引用

页码：14 / 16

页数：3

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