Gold-Catalyzed Synthesis of Glyoxals by Oxidation of Terminal Alkynes: One-Pot Synthesis of Quinoxalines

被引：131
作者：
Shi, Shuai [1 ]
Wang, Tao [1 ]
Yang, Weibo [1 ]
Rudolph, Matthias [1 ]
Hashmi, A. Stephen K. [1 ]
机构：
[1] Heidelberg Univ, Inst Organ Chem, D-69120 Heidelberg, Germany
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 21期
关键词：
glyoxals; gold catalysis; N-oxides; oxidation; quinoxalines; SELENIUM DIOXIDE; MILD OXIDATION; METHYL KETONES; DERIVATIVES; REARRANGEMENT; CONVENIENT; ALDEHYDES; ALCOHOLS;
D O I：
10.1002/chem.201300518
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
From terminal alkynes to glyoxals: Terminal alkynes can be oxidized under mild conditions by the use of an N-oxide in the presence of a gold catalyst. The intermediate glyoxal derivatives can be transferred in a one-pot procedure to substituted quinoxalines (see scheme). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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收藏
页码：6576 / 6580
页数：5
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