Breastfeeding by Women Living With Human Immunodeficiency Virus in a Resource-Rich Setting: A Case Series of Maternal and Infant Management and Outcomes

被引:25
作者
Nashid, N. [1 ,2 ]
Khan, S. [3 ]
Loutfy, M. [4 ,5 ]
MacGillivray, J. [6 ,7 ]
Yudin, M. H. [6 ,8 ]
Campbell, D. M. [2 ,9 ]
Barozzino, T. [2 ,9 ]
Baqi, M. [10 ]
Read, S. E. [1 ,2 ]
Bitnun, A. [1 ,2 ]
机构
[1] Hosp Sick Children, Dept Pediat, Toronto, ON, Canada
[2] Univ Toronto, Dept Pediat, Toronto, ON, Canada
[3] McMaster Univ, Hamilton Hlth Sci Ctr, Dept Pediat, Hamilton, ON, Canada
[4] Univ Toronto, Dept Med, Toronto, ON, Canada
[5] Womens Coll Hosp, Womens Coll Res Inst, Toronto, ON, Canada
[6] St Michaels Hosp, Dept Obstet & Gynecol, Toronto, ON, Canada
[7] Ryerson Univ, Midwifery Educ Program, Toronto, ON, Canada
[8] Univ Toronto, Dept Obstet & Gynecol, Toronto, ON, Canada
[9] St Michaels Hosp, Dept Pediat, Toronto, ON, Canada
[10] William Osler Hlth Syst, Dept Med, Toronto, ON, Canada
基金
加拿大健康研究院;
关键词
breastfeeding; child; combination an antiretroviral therapy; HIV; prevention; ANTIRETROVIRAL THERAPY; HIV-1; TRANSMISSION; MILK CELLS; PREVENTION; NEVIRAPINE; PROPHYLAXIS; LAMIVUDINE; SAFETY;
D O I
10.1093/jpids/piz003
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The reduction in human immunodeficiency virus (HIV) transmission through breastmilk with maternal combination antiretroviral therapy (cART) has led many pregnant women living with HIV and healthcare providers to question exclusive formula feeding in resource-rich settings. Here, we describe cART prophylaxis in 3 breastfed infants whose mothers had sustained virologic suppression; all 3 of these infants remained uninfected.
引用
收藏
页码:228 / 231
页数:4
相关论文
共 21 条
[1]   Postnatal HIV transmission in breastfed infants of HIV-infected women on ART: a systematic review and meta-analysis [J].
Bispo, Stephanie ;
Chikhungu, Lana ;
Rollins, Nigel ;
Siegfried, Nandi ;
Newell, Marie-Louise .
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2017, 20
[2]   Prevention of vertical HIV transmission and management of the HIV-exposed infant in Canada in 2014 [J].
Bitnun, Ari ;
Brophy, Jason ;
Samson, Lindy ;
Alimenti, Ariane ;
Kakkar, Fatima ;
Lamarre, Valerie ;
Moore, Dorothy ;
Karatzios, Christos ;
Seigel, Sandra ;
Sauve, Laura ;
Vaudry, Wendy ;
Yudin, Mark H. ;
Money, Deborah .
CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY, 2014, 25 (02) :75-77
[3]  
British HIV Association, 2018, BRIT HIV ASS GUID MA
[4]   The rate of mother-to-child transmission of antiretroviral drug-resistant HIV strains is low in the Swiss Mother and Child HIV Cohort Study [J].
Compagno, Francesca ;
Naegele, Klaudia ;
Kahlert, Christian R. ;
Hosli, Irene ;
Aebi-Popp, Karoline ;
de Tejada, Martinez Begona ;
Paioni, Paolo ;
Yerly, Sabine ;
Boni, Jurg ;
Battegay, Manuel ;
Rudin, Christoph ;
Hirsch, Hans H. ;
Anagnostopoulos, A. ;
Asner, S. ;
Baumann, M. ;
Furrer, H. ;
Fux, C. A. ;
Grawe, C. ;
Gunthard, H. F. ;
Haerry, D. ;
Hasse, B. ;
Hoffmann, M. ;
Huber, M. ;
Kaiser, L. ;
Keiser, O. ;
Klimkait, T. ;
Kottanattu, L. ;
Kouyos, R. D. ;
Kovari, H. ;
Ledergerber, B. ;
Martinetti, G. ;
Marzolini, C. ;
Metzner, K. J. ;
Mueller, N. ;
Nicca, D. ;
Pantaleo, G. ;
Perreau, M. ;
Polli, Ch ;
Rauch, A. ;
Scherrer, A. U. ;
Schmid, P. ;
Speck, R. ;
Stockle, M. ;
Tarr, P. ;
Thanh, Lecompte M. ;
Vernazza, P. ;
Wagner, N. ;
Wandeler, G. ;
Weber, R. ;
Wyler, C. A. .
SWISS MEDICAL WEEKLY, 2019, 149
[5]  
Flynn P, 2018, 22 INT AIDS C JUL 23
[6]   Prevention of HIV-1 Transmission Through Breastfeeding: Efficacy and Safety of Maternal Antiretroviral Therapy Versus Infant Nevirapine Prophylaxis for Duration of Breastfeeding in HIV-1-Infected Women With High CD4 Cell Count (IMPAACT PROMISE): A Randomized, Open-Label, Clinical Trial [J].
Flynn, Patricia M. ;
Taha, Taha E. ;
Cababasay, Mae ;
Fowler, Mary Glenn ;
Mofenson, Lynne M. ;
Owor, Maxensia ;
Fiscus, Susan ;
Stranix-Chibanda, Lynda ;
Coutsoudis, Anna ;
Gnanashanmugam, Devasena ;
Chakhtoura, Nahida ;
McCarthy, Katie ;
Mukuzunga, Cornelius ;
Makanani, Bonus ;
Moodley, Dhayendre ;
Nematadzira, Teacler ;
Kusakara, Bangini ;
Patil, Sandesh ;
Vhembo, Tichaona ;
Bobat, Raziya ;
Mmbaga, Blandina T. ;
Masenya, Maysseb ;
Nyati, Mandisa ;
Theron, Gerhard ;
Mulenga, Helen ;
Butler, Kevin ;
Shapiro, David E. .
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2018, 77 (04) :383-392
[7]  
Flynn PM, 2018, 10 WORKSH HIV PED JU
[8]   Prevalence and dynamics of the K65R drug resistance mutation in HIV-1-infected infants exposed to maternal therapy with lamivudine, zidovudine and either nevirapine or nelfinavir in breast milk [J].
Inzaule, Seth C. ;
Weidle, Paul J. ;
Yang, Chunfu ;
Ndiege, Kenneth ;
Hamers, Raph L. ;
de Wit, Tobias F. Rinke ;
Thomas, Timothy ;
Zeh, Clement .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2016, 71 (06) :1619-1626
[9]   Should Providers Discuss Breastfeeding With Women Living With HIV in High-Income Countries? An Ethical Analysis [J].
Johnson, Grace ;
Levison, Judy ;
Malek, Janet .
CLINICAL INFECTIOUS DISEASES, 2016, 63 (10) :1368-1372
[10]   Safety of combination antiretroviral prophylaxis in high-risk HIV-exposed newborns: a retrospective review of the Canadian experience [J].
Kakkar, Fatima W. ;
Samson, Lindy ;
Vaudry, Wendy ;
Brophy, Jason ;
Le Meur, Jean-Baptiste ;
Lapointe, Normand ;
Read, Stanley E. ;
Bitnun, Ari .
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2016, 19